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The Catecholaminergic Innervation of the Rat Amygdala: Advances in Anatomy, Embryology and Cell Biology, cartea 142

Autor Esther Asan
en Limba Engleză Paperback – 18 mar 1998

Din seria Advances in Anatomy, Embryology and Cell Biology

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Specificații

ISBN-13: 9783540639039
ISBN-10: 3540639039
Pagini: 136
Ilustrații: XII, 121 p. 36 illus., 1 illus. in color.
Dimensiuni: 155 x 235 x 7 mm
Greutate: 0.2 kg
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Advances in Anatomy, Embryology and Cell Biology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

1 Introduction.- 2 Materials and Methods.- 2.1 Tissue Preparation.- 2.2 Immunocytochemistry.- 2.3 In Situ Hybridization.- 3 Results and Discussions.- 3.1 Cytoarchitectonics.- 3.2 Comparative Light, Fluorescence, and Electron-Microscopic Studies of the Morphology and Neurochemistry of Catecholaminergic Afferent Fibers to the Amygdala.- 3.2.3 Conclusions for the Identification of Dopaminergic, Noradrenergic, and Adrenergic Structures.- 3.3 Ultrastructural Features of Neurons and Catecholaminergic Afferent Fibers in the Nucleus Centralis, the Basal Complex, and the Paracapsular Intercalated Cell Groups.- 3.4 Colocalization of Neuropeptides in Catecholaminergic Afferent Fibers to the Amygdala.- 3.5 Neurochemical Characterization of Possible Target Neurons of the Catecholaminergic Amygdala Innervation.- 4 Summary.- 4.1 Conclusions for the Individual Amygdaloid Nuclei.- 4.2 Conclusions for the Different Types of Catecholaminergic Innervation.- 5 References.

Textul de pe ultima copertă

Experimental evidence indicates that catecholamines are able to modulate information processing in the amygdaloid complex. The dense catecholaminergic innervation of the amygdala may thus exert significant influence upon its well-documented functions in emotion, attention, learning and memory. Dysfunctions of the systems have been suggested to be involved in the etiology of neuropsychiatric disorders including senile dementia, Parkinson's disease and schizophrenia. To further insight into neural mechanisms of the innervation, the present study provides a detailed documentation of ultrastructural and neurochemical characteristics of dopanminergic, noradrinergic and adrenergic afferent fibers and of their target structures in central, basal and intercalated amygdaloid nuclei. A high degree of heterogeneitiy is observed between the nuclei concerning the different catecholaminergic innervation patterns and the peptide content of individual catecholaminergic fibers, as well as concerning the neurotransmitter/-modulator and receptor expression of possible amygdaloid target neurons. The results are discussed with regard to previously documented properties of the nuclei.