The Design of Covalent-Based Inhibitors: Annual Reports in Medicinal Chemistry, cartea 56
Richard A. Ward, Neil Grimsteren Limba Engleză Hardback – 8 iul 2021
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Specificații
ISBN-13: 9780128216897
ISBN-10: 0128216891
Pagini: 298
Dimensiuni: 152 x 229 x 20 mm
Greutate: 0.57 kg
Editura: ELSEVIER SCIENCE
Seria Annual Reports in Medicinal Chemistry
ISBN-10: 0128216891
Pagini: 298
Dimensiuni: 152 x 229 x 20 mm
Greutate: 0.57 kg
Editura: ELSEVIER SCIENCE
Seria Annual Reports in Medicinal Chemistry
Public țintă
Undergraduates, graduates, academics, and researchers in the field of medicinal chemistryCuprins
Preface Richard Andrew Ward and Neil Grimster 1. The history of covalent inhibitors Renato A. Bauer 2. Kinetic Mechanisms of Covalent Inhibition Claire Louise McWhirter 3. Covalent Drugs in Development for Immune-Mediated Diseases Leonard Sung 4. Chemistry Perspectives of Reversible Covalent Drugs Jianmin Gao 5. Design of Next-Generation Covalent Inhibitors: Targeting Residues Beyond Cysteine Lyn Jones 6. Boron and Covalent Inhibition Andrew Leach 7. Measuring and predicting warhead and residue reactivity Christopher Rowley 8. Computational Support of Structure-based Targeted Covalent Inhibitor Design Robert Abel 9. Novel approaches to covalent inhibition Nir London 10. The future of covalent inhibition Gyorgy M. Keseru