Five years ago, Orlando Duncan created the perfect drug in HEAT. It made the Duncans more than two hundred and fifty million dollars and was on its way to making them billionaires. However, they abruptly stopped manufacturing the drug when it was proven to cause cancer in rats. When Orlando is awakened by an alarm in his old lab, he discovers that not only have all his computers, equipment, and notes been stolen, but the robbers have also taken over a million tabs of HEAT that he'd left behind for future experiments - tabs that he had sworn to his family he would destroy.