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The Human Hypothalamus: Neuroendocrine Disorders: Handbook of Clinical Neurology, cartea 181

Editat de Dick F. Swaab, Ruud M. Buijs, Paul J. Lucassen, Ahmad Salehi, Felix Kreier
en Limba Engleză Hardback – 21 sep 2021
The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders.

  • Discusses the importance of the hypothalamus in human growth and development
  • Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders
  • Includes metabolic and eating disorders
  • Identifies mechanisms of disease action and etiology
  • Provides best practice information for assessment and treatment
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Specificații

ISBN-13: 9780128206836
ISBN-10: 0128206837
Pagini: 566
Dimensiuni: 195 x 260 mm
Editura: ELSEVIER SCIENCE
Seria Handbook of Clinical Neurology


Public țintă

Clinical neurologists, researchers in neurology

Cuprins

1. Introduction: The human hypothalamus and neuroendocrine disorders
SECTION 15  Structural disorders of the hypothalamo-pituitary region
2. Pituitary stalk interruption syndrome 
3. Empty sella syndrome: Multiple endocrine disorders 
4. Pituitary dysfunction after aneurysmal subarachnoidal hemorrhage
5. Septo-optic dysplasia 
SECTION 16  Tumors of the hypothalamus
6. Hypothalamic hormone-producing tumors 
7. Craniopharyngiomas primarily affecting the hypothalamus 
SECTION 17  Neuroimmunological disorders
8. The stress-axis in multiple sclerosis: Clinical, cellular, and molecular aspects 
9. Neuroendocrine manifestations of Langerhans cell histiocytosis 
10. Neuroendocrine manifestations of Erdheim–Chester disease
11. Hypothalamitis and pituitary atrophy 
12. Narcolepsy Type I as an autoimmune disorder 
13. Neuromyelitis optica, aquaporin-4 antibodies, and neuroendocrine disorders
14. Antibodies against the pituitary and hypothalamus in boxers
15. Autoimmune diabetes insipidus 
SECTION 18  Drinking disorders
16. Neuroimaging of central diabetes insipidus 
17. Differential diagnosis of familial diabetes insipidus
18. The vasopressin–aquaporin-2 pathway syndromes 
19. Adipsic diabetes insipidus 
20. Animal models for diabetes insipidus 
21. Nocturnal enuresis in children: The role of arginine–vasopressin
SECTION 19  Eating disorders
22. Monogenic human obesity syndromes
23. Hypothalamic microinflammation 
24. Glucose and fat sensing in the human hypothalamus 
25. Hypothalamus and neuroendocrine diseases: The use of human-induced pluripotent stem cells for disease modeling 
26. Prader–Willi syndrome: Hormone therapies
27. Transcriptomics of the Prader–Willi syndrome hypothalamus 
28. Disorders of hypothalamic function: Insights from Prader–Willi syndrome and the effects of craniopharyngioma 
29. Animal models for Prader–Willi syndrome 
30. Is there a hypothalamic basis for anorexia nervosa? 
SECTION 20   Reproduction, olfaction and sexual behavior
31. Sexual differentiation of the human hypothalamus: Relationship to gender identity and sexual orientation
32. Klinefelter syndrome or testicular dysgenesis: Genetics, endocrinology, and neuropsychology
33. Neurobiology of puberty and its disorders