Describes activities underway in 2009 and planned for 2010 by Federal agencies participating in the National Nanotechnology Initiative (NNI), primarily from a programmatic and budgetary perspective. It is based on the NNI Strategic Plan released in December 2007 and reports estimated investments for 2009 and requested investments for 2010 by Program Component Area (PCA), as called for under provisions of the 21st Century Nanotechnology Research and Development Act (Public Law 108-153).