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The Neuregulin-I/ErbB Signaling System in Development and Disease de Stefan Britsch

The Neuregulin-I/ErbB Signaling System in Development and Disease: Advances in Anatomy, Embryology and Cell Biology, cartea 190

Autor Stefan Britsch
en Limba Engleză Paperback – 9 mar 2007

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Specificații

ISBN-13: 9783540371052
ISBN-10: 3540371052
Pagini: 70
Ilustrații: XI, 70 p.
Dimensiuni: 155 x 235 x 7 mm
Greutate: 0.13 kg
Ediția:2007
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Advances in Anatomy, Embryology and Cell Biology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

Introduction – Molecular control of development.- Biology of the Neuregulin/ErbB signaling network.- Neuregulins and their receptors.- Developmental functions of the Neuregulin-1/ErbB signalling pathway.- Interacting molecules – the Sox10/ErbB connection.- NRG-1/ErbB signals and disease.- Abbreviations.- References.- Subject index

Textul de pe ultima copertă

Neuregulins are EGF-like growth and differentiation factors that interact with tyrosine kinase receptors of the ErbB family. this signailing system has a wide range of functions during development of the nervous system, the heart, and the mammary gland. Furthermore, Neuregulin signals are also involved in the development of human diseases including breast cancer, heart disease and the pathogenesis of schizophrenia.
This monograph reviews the biology of Neuregulins and their receptors and summarizes recent research, which has established crucial functions of this signaling system during development and disease.