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The Steric Factor in Medicinal Chemistry: Dissymmetric Probes of Pharmacological Receptors

Autor A.F. Casy
en Limba Engleză Paperback – 22 iun 2013
'It is indeed the merit of Dr. Alan F. Casy to bring in these pages a clear and comprehensive view of medicinal stereochemistry, a discipline in which he has been active and successful for many years both as a teacher and a researcher. Written for graduate students and research workers in medicinal chemistry and pharmacology, this book will contribute significantly towards a better education of scientists by removing the fear of stereochemistry caused by ignorance, moderating the overconfidence of possible zealots, and outlining a broader context.'-from the foreword by Bernard Testa
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Specificații

ISBN-13: 9781489923998
ISBN-10: 1489923993
Pagini: 592
Ilustrații: XX, 570 p.
Dimensiuni: 155 x 235 x 31 mm
Greutate: 0.82 kg
Ediția:Softcover reprint of the original 1st ed. 1993
Editura: Springer Us
Colecția Springer
Locul publicării:New York, NY, United States

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Research

Cuprins

1. Introduction.- 2. Nomenclature and Methodology.- 3. Pharmacokinetics: Including Use of Racemic Mixtures in Therapy.- 4. Adrenergic Ligands: Chiefly Agonists.- 5. Adrenoceptor Antagonists.- 6. Dopamine and Dopaminergic Ligands.- 7. Dopamine Antagonists.- 8. Cholinergic Agonists.- 9. Muscarinic Antagonists.- 10. Ligands of Nicotinic Cholinergic Receptors (nAChR) Including Neuromuscular Blocking Agents.- 11. Histamine Receptors: Agonists and Antagonists.- 12. 5-Hydroxytryptamine Ligands.- 13. Opioid Ligands: Part 1.- 14. Opioid Ligands: Part 2.- Appendix and Postscript.