The thesis in the book starts with questioning existing postulates and introducing one new postulate: Nothing exists in isolation, i.e. everything exists in relations. Then, based on this postulate, a principle is formulated and a theory that takes us further and deeper into the physical reality. 1. The thesis is that in the physical reality continuous flows of packages moves in "tubes" between all systems resulting in gravitation, force and energy. These flows contain all mass in Universe, including dark matter and dark energy, i.e. the same principle rules at all levels of the physical reality. 2. The equation E=mc2 is inquired, where Einstein s own criterion for a complete theory that "every element of the physical reality must have a counterpart in the physical theory", raises the question which element the concept c2 has in the physical reality. How do we deal with this contradiction? 3. The principle of relations launces a new explanation of the equation E=mc2, which has impacts on the general theory of relativity and then it is possible with a new interpretation of gravitation, which is demonstrated. 4. In the last chapter everything ends in one formula (equation), which is the most important dealing with the theoretical foundation of physical reality, uniting the theories of relativity and quantum, with dark matter and dark energy. Whether you're ready for a new perspective on the world or not, this book will provoke your brain into reexamining everything you think you know about the physical reality.