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Toxicologic Pathology for Non-Pathologists de Thomas J. Steinbach

Toxicologic Pathology for Non-Pathologists

Editat de Thomas J. Steinbach, Daniel J. Patrick, Mary Ellen Cosenza
en Limba Engleză Hardback – 30 oct 2019
This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances. 

Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.
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Specificații

ISBN-13: 9781493997763
ISBN-10: 1493997769
Pagini: 788
Ilustrații: X, 919 p. 228 illus., 208 illus. in color.
Dimensiuni: 178 x 254 mm
Greutate: 1.77 kg
Ediția:1st ed. 2019
Editura: Springer
Colecția Humana
Locul publicării:New York, NY, United States

Cuprins

1. Introduction to Toxicologic Pathology
            George A. Parker
 
2. The Pathology Report, Peer Review, and Pathology Working Group
            Ted A. Birkebak and Peter C. Mann
 
3. Routine and Special Techniques in Toxicologic Pathology            Pamela Blackshear, Erica Carroll, Sasmita Mishra, Matthew Renninger, and Arun Tatiparthi
 
4. Pathology of the Liver and Gallbladder
            Robert R. Maronpot and David E. Malarkey
 
5. Pathology of the Gastrointestinal Tract and Exocrine Pancreas            Mark J. Hoenerhoff and Arun Kumar R. Pandiri
 
6. Pathology of the Urinary System
            Kendall S. Frazier
 
7. Pathology of the Nervous System
            Juliana S. Lee, Sarah D. Cramer, and Mark T. Butt
 
8. Pathology of the Cardiovascular System
            Joshua H. Decker, Radhakrishna Sura, and Paul W. Snyder
 
9. Pathology of the Respiratory System
            Jack R. Harkema and James G. Wagner
 
10. Pathology of the Lymphoid System
            Tracey L. Papenfuss, Marlon C. Rebelatto, and Brad Bolon
 
11. Pathology of the Male and Female Reproductive System and Mammary Gland
            Justin D. Vidal
 
12. Pathology of the Integumentary System
            Kelly L. Diegel
 
13. Pathology of the Endocrine System
            Brent E. Walling and Thomas J. Rosol
 
14. Pathology of Bone, Skeletal Muscle, and Tooth
            Stacey Fossey, D. Greg Hall, Andrew Suttie, Martin Guillot, and Aurore Varela
 
15. Pathology of the Eye
            Leandro B.C. Teixeira
 
16. Pathology of the Ear
            Kenneth A. Schafer
 
17. Principles of Toxicologic Clinical Pathology
            Adam Aulbach and Laura Cregar
 
18. Carcinogenicity
            Paul Howroyd
 
19. Pathology of Juvenile Animals
            Catherine A. Picut and Amera K. Remick
 
20. Non-Mammalian Laboratory Species: Fish, Frogs, and Beyond
            Shannon Wallace and Jeff Wolf
 
 
Appendix: Fundamental Pathology Terminology Based on the Standard for the Exchange of Nonclinical Data (SEND)

Notă biografică

Thomas J. Steinbach DVM, DACVP, DABT (Experimental Pathology Laboratories, Inc., Research Triangle Park, NC, USA) and Daniel J. Patrick DVM, DACVP, DABT (Charles River Laboratories, Inc., Mattawan, MI, USA) have worked for numerous years to help organize the successful "Pathology for Non-Pathologists" short course, created with the support of the American College of Toxicology (ACT) and Society of Toxicologic Pathology (STP), upon which this book is based. Mary Ellen Cosenza PhD, DABT, RAC, ATS (MEC Regulatory & Toxicology Consulting, LLC, Moorpark, CA, USA) was an inaugural committee member of this short course and remains a highly respected member of the community at large.

Textul de pe ultima copertă

This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances. 

Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.

Caracteristici

Provides practical guidance for non-pathologists in the complex field of pathology
Based on a successful course supported by the ACT and STP
Serves as a tool for aiding toxicologists to converse in the language of pathology