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Tumor Immunology: Immunotherapy and Cancer Vaccines: Cancer: Clinical Science in Practice

Editat de A. G. Dalgleish, M. J. Browning Cuvânt înainte de Karol Sikora
en Limba Engleză Paperback – 24 noi 2010
This 1996 volume reviewed advances in the field of human tumour immunology, particularly in relation to the potential for immune intervention in preventing or treating tumours. The editors and contributors, all prominent workers in the field, survey advances in the understanding of the relationship between the cancer cell and the immune response at the time of publication. Chapters review in depth the function of immune surveillance and mechanisms of tumour immunity, the role of T lymphocytes and oncogenes in the immune response to cancer, and the potential for immunotherapy of cancer. Areas of tumour immunology that were new at the time of this book's publication are presented, including progress in the development of tumour vaccines with particular reference to melanoma. The volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer.
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Specificații

ISBN-13: 9780521159470
ISBN-10: 0521159474
Pagini: 374
Dimensiuni: 152 x 229 x 21 mm
Greutate: 0.55 kg
Editura: Cambridge University Press
Colecția Cambridge University Press
Seria Cancer: Clinical Science in Practice

Locul publicării:New York, United States

Cuprins

Contributors; Series Editor's Preface; Abbreviations; 1. Introduction and historical perspectives Michael Browning and A. G. Dalgleish; 2. The immunosurveillance of cancer: specific and non-specific mechanisms Richard G. Vile, Heung Chong and Sina Dorudi; 3. Antigen processing and presentation Nicholas C. Testifo and Michael Wang; 4. The role of the MHC class I in tumor immunity Michael Browning; 5. Human tumor antigens recognized by Cytolytic T Lymphocytes Pierre G Coulie; 6. Peptide-specific CTL directed against viral oncogene products Mariet C.W. Feltkamp, Cornelis J. M. Melief and W. Martin Kast; 7. Cellular oncogenes for tumor immunity: immunotherapy Hans J. Strauss and A. Maria Dahl; 8. Co-stimulatory molecules and their role in tumour immunity A. G. Dalgleish; 9. The role of cytokines in tumour rejection Guido Forni and Robin Foa; 10. Inhibition of nonhemopoietic cancer cell growth by Interleukin-4 and related cytokines Dave S. B. Hoon, Takashi Morisaki and Richard Essner; 11. Current concepts concerning melanoma vaccines Donald L. Morton and Mepur H. Ravindranath; 12. Immune responses to mucins Rosalind A. Graham and Joyce Taylor-Papadimitriou; 13. Heat shock protein-peptide complexes: pan-valent vaccines against cancers and infectious diseases Ryuichiro Suto and Pramod K. Srivastave; 14. The potential of gene transfer to alter the immune response to tumors Bernard A. Fox and Gary J. Nabel; 15. Applications of antibody gene technology Robert E. Hawkins and Kerry A. Chester; Index.

Recenzii

Review of the hardback: ' … will serve as a good text-book on cancer immunology and/or an excellent reference source on its individual topics. It can be recommended to clinicians, researchers and even undergraduates wishing to deepen their knowledge of this field.' Anton B. Alexandfoff, Immunology News
Review of the hardback: ' … an excellent source of information which will be most helpful to the clinicians involved or interested in the various clinical vaccine trials that have been or will be implemented in the next five years.' J.-C. Cerottini, Annals of Oncology
Review of the hardback: ' … there is much to commend the book. It will appeal mainly to clinicians and scientists who have some basic knowledge of cancer and immunology.' J. A. Ledermann, Journal of the Royal Society of Medicine
Review of the hardback: ' … a balanced overview of the state-of-the-art, with special emphasis on the new potential for cancer immunotherapy … an excellent source of information'. Annals of Oncology

Descriere

This 1996 volume reviewed advances in the field of human tumour immunology for an audience of clinicians and researchers.