Viral Regulatory Structures And Their Degeneracy

Preface -- Introduction -- Regulation of the Papillomavirus E6 and E7 Oncoproteins By the Viral E1 and E2 Proteins -- The Control of Human Papillomavirus Transcription -- Transcriptional Regulation of HIV -- Role and Mechanism of Action of the HIV-1 Rev Regulatory Protein -- Posttranscriptional Control: A General and Important Regulatory Feature of HIV-1 and Other Retroviruses -- Posttranscriptional Regulation of Papillomavirus Gene Expression -- Questions About RNA Structures in HIV and HPV -- Sequence Redundancy in Biopolymers: A Study on RNA and Protein Structures -- Plurality in HIV Genetics -- Combinatorial Approaches to Inhibiting the HIV Rev-RRE Interaction -- States, Trajectories, and Attractors: A Genetic Networks Perspective of Viral Pathogenesis -- Some Reflections on Complexities in Understanding Virus Biology

This book focuses on the nature, origins, and degeneracy (or redundancy) of viral regulatory elements and on the strategies that enable viruses to adapt to cells, examining experimental findings and models regarding HIV and HPV regulatory mechanisms.