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AMP-activated Protein Kinase de Mario D. Cordero

AMP-activated Protein Kinase: Experientia Supplementum, cartea 107

Editat de Mario D. Cordero, Benoit Viollet
en Limba Engleză Hardback – 28 noi 2016
AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes.
This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease. 
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Specificații

ISBN-13: 9783319435879
ISBN-10: 3319435876
Pagini: 410
Ilustrații: X, 523 p. 55 illus., 42 illus. in color.
Dimensiuni: 155 x 235 x 30 mm
Greutate: 0.92 kg
Ediția:1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Seria Experientia Supplementum

Locul publicării:Cham, Switzerland

Cuprins

Part I: AMPK in health.- Structure and Regulation of AMPK.- AMPK Regulation of Carbohydrate Metabolism.- AMPK Regulation of Lipid Metabolism.- AMPK Regulation of Protein Metabolism.- AMPK Regulation of cell growth, apoptosis, autophagy and bioenergetics.- AMPK Regulation of immunology.- AMPK and Stem Cells.- Part II: AMPK in the diseases.- AMPK in metabolic diseases.- AMPK in neurodegenerative diseases.- AMPK in cardiovascular diseases.- AMPK in cancer.- AMPK in aging.- AMPK in musculoskeletal diseases and pain.- AMPK in pathogens.- Part III: Pharmacology of AMPK.- Metformin, new drugs and AMPK.- Small molecules and AMPK.- Nutraceutical compounds and AMPK.- Part IV: Methods of study in AMPK.- Animal models.- In vitro study methods.

Notă biografică

Mario D Cordero is Research Associate at the University of Sevilla, Laboratory of Biological Research. He studies the role of AMPK in the metabolic abnormalities of the central nervous system in psychiatric diseases, and the implication of AMPK in the mechanism of pain and inflammation. He is also involved in drug trials using AMPK activators in rare diseases.
 
 
Benoit Viollet leads a research team at the Institut Cochin, Paris, which studies the physiological role of AMPK in cellular energy balance and the integrated stress response such as exercise, as well as nutrient and hormonal signals. The work includes studies of the therapeutic opportunity of AMPK in metabolic abnormalities associated with type 2 diabetes and obesity.
 

Textul de pe ultima copertă

AMPK has emerged as an important integrator of signals that control energy balance through the regulation of multiple biochemical pathways in eukaryotes.
This book focuses on the implications of AMPK as a master metabolic regulator in diseases, including new methods and animal models. The contributions are written by leading experts in the field and give an extensive overview of the current knowledge of AMPK biology and the role of AMPK in health and disease. 

Caracteristici

Extensive coverage of the role of AMPK as master regulator of cell energy levels in disease and aging Presents new methods and animal models for the study of this enzyme Includes effects of drugs and nutraceutical compounds