Hepatic De Novo Lipogenesis and Regulation of Metabolism
Editat de James M. Ntambien Limba Engleză Hardback – 28 dec 2015
With the current epidemic of metabolic diseases, it is of immediate importance to understand the contribution of the liver in health and its role in the development of impaired metabolic regulation. This book covers the many studies that have unmasked important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases.
One of the major metabolic functions of the liver is to carry out de novo lipogenesis, which is the metabolic pathway that allows the conversion of excess carbohydrates into fatty acids. The process of de novo lipogenesis is covered in depth within this volume. The book is an important contribution to the vast literature and ongoing research on liver function.
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Specificații
ISBN-13: 9783319250632
ISBN-10: 3319250639
Pagini: 305
Ilustrații: XI, 305 p. 35 illus., 5 illus. in color.
Dimensiuni: 155 x 235 x 18 mm
Greutate: 0.76 kg
Ediția:1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland
ISBN-10: 3319250639
Pagini: 305
Ilustrații: XI, 305 p. 35 illus., 5 illus. in color.
Dimensiuni: 155 x 235 x 18 mm
Greutate: 0.76 kg
Ediția:1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Locul publicării:Cham, Switzerland
Public țintă
ResearchCuprins
Transcriptional Regulation of De Novo Lipogenesis in Liver.- The Molecular Basis of Hepatic De Novo Lipogenesis in Insulin Resistance.- Regulation of Hepatic Metabolism by the Mechanistic Target of Rapamycin.- FoxO1: A Conductor of Insulin Signaling to Glucose and Lipid Metabolism.- Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease.- Role of the Endocannabinoid System in Hepatic Lipogenesis.- Role of Lipogenesis and Lipid Desaturases in Non-Alcoholic Fatty Liver Disease.- Lipid Droplet Proteins and Lipid Metabolism.- Influence of Gut Microbiota on Hepatic Lipogenesis and Disease Pathogenesis.- Hepatic Lipogenesis: Nutritional Control and Pathophysiological Relevance.- Metabolic Rhythm of Hepatic Lipogenesis: Regulation and Roles in Metabolism.- Monounsaturated Fatty Acid Mediated Liver-adipose Tissue Crosstalk and Metabolic Regulation.- Adipose Tissue DNL and Its Role in Metabolic Homeostasis.- The Lipogenic Effect of Insulin Revisited.- Index.
Notă biografică
James M. Ntambi, PhD, is the Katherine Berns Von Donk Steenbock Professor in Nutrition, Department of Chemistry, College of Agricultural and Life Sciences, at the University of Wisconsin, Madison.
Caracteristici
Expert contributors offer all the primary and relevant metabolic information the reader needs to review to understand the complex and diverse role of the liver in metabolism
Discusses dietary nutrients and the effect they have on the epigenetic regulation of genes
Covers the many studies that have unmasked the important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases
Includes supplementary material: sn.pub/extras
Discusses dietary nutrients and the effect they have on the epigenetic regulation of genes
Covers the many studies that have unmasked the important roles that proteins expressed in the liver play in the development of or protection from metabolic diseases
Includes supplementary material: sn.pub/extras