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Animal Lectins: A Functional View

Editat de Gerardo R. Vasta PhD, Hafiz Ahmed PhD
en Limba Engleză Hardback – 9 oct 2008
Introduces Groundbreaking Approaches for Assessing Lectin Function
Lectins and their ligands are under quite a heavy microscope due to their potential applications to pharmacology, immunology, cancer therapy, and agriculture. With growing interest in the glycobiology field, the body of research related to lectin roles has grown at an explosive rate, particularly in the past 20 years. Animal Lectins: A Functional View presents the most up-to-date analysis of these carbohydrate-binding, and potentially lifesaving, proteins in one comprehensive volume.
This standard-setting resource presents new insights into the biological roles of most animal lectins, including their function in infection prevention through innate immunity. It also discusses such lectin behaviors as:
  • Glycoprotein folding
  • Sorting and targeting
  • Cell adhesion
  • Embryogenesis
  • Cell-cell interactions and signaling
Describes the Structural Basis of Protein-Carbohydrate Interactions
Under the editorial guidance of two leading protein chemistry experts and with contributions from well-recognized field authorities, this book logically and systematically discusses both intracellular and extracellular lectin functions. It is an essential springboard for future field research and a clear and concise knowledge base that glycobiology, biochemistry, and immunology researchers cannot afford to be without.
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Specificații

ISBN-13: 9780849372698
ISBN-10: 0849372690
Pagini: 596
Ilustrații: 129 b/w images, 23 tables and 34 halftones
Dimensiuni: 178 x 254 x 33 mm
Greutate: 1.13 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Professional

Cuprins

INTRODUCTION. MODERN APPROACHES FOR ASSESSING LECTIN FUNCTION. GLYCOPROTEIN FOLDING, SORTING AND SECRETION, TARGETING, DEGRADATION, AND CLEARANCE. CELL ADHESION AND CELL SURFACE LATTICE FORMATION. CELL–CELL INTERACTIONS, SIGNALING, AND TRANSPORT. RECOGNITION AND EFFECTOR FUNCTIONS IN INNATE IMMUNITY.

Notă biografică

Gerardo R. Vasta PhD, Hafiz Ahmed PhD

Descriere

Lectins are currently of interest in the research community because of their wide variety of properties and potential applications in pharmacology, immunology, and cancer therapy. Identifying lectins and their ligands is the particular focus of intense study. Featuring contributions from recognized experts, Animal Lectins: A Functional View presents up-to-date knowledge of the biological roles of animal lectins, including glycoprotein folding, sorting, and targeting; cell adhesion; embryogenesis; cell-cell interactions and signaling; as well as recognition and effector functions in innate immunity. This book also explores the structural basis of protein-carbohydrate interactions.