Antianginal Drugs: Pathophysiological, Haemodynamic, Methodological, Pharmacological, Biochemical and Clinical Basis for Their Use in Human Therapeutics: Handbook of Experimental Pharmacology, cartea 31

Coronary Atherosclerosis: General Considerations.- Epidemiology of Coronary Atherosclerosis.- Clinical Manifestations of Coronary Atherosclerosis.- General Therapeutic Measures in Angina Pectoris.- Physical Training in Angina Pectoris.- Treatment of Determining Factors of Atherosclerosis — of Formed Anatomical Lesions: Surgery.- — of Predisposing Factors.- — of the Anginal Syndrome.- I. Pathophysiology of Angina Pectoris.- 1. Pathophysiology of the Anginal Attack.- 2. Cardiac Dynamics during the Anginal Attack.- 3. Part Played by Hypersympathicotony in the Anginal Attack.- 4. Trends in Pharmacological Research for the Development of Antianginal Medications.- II. Haemodynamic Basis for Coronary Pharmacology.- General Considerations.- Blood Pressure.- Myocardial Oxygen Consumption.- Cardiac Work.- Cardiac Output.- Heart Rate.- Regulation of Coronary Circulation.- III. Pharmacological Methodology for Testing Antianginal Drugs.- Coronary Blood Flow.- 1. Measurement of Coronary Outflow.- 2. Measurement of Coronary Inflow.- 3. Nutritional Myocardial Micro-Circulation.- 4. Collateral Coronary Circulation.- 5. Experimental Chronic Coronary Insufficiency.- Measuring Cardiac Output.- Measuring Cardiac Work.- Measuring Myocardial Oxygen Consumption.- IV. Clinical Methods for Assessment of the Therapeutic Value of Antianginal Medications.- Diagnosis of Angina Pectoris.- Clinical Assessment of Antianginal Drugs.- V. Pharmacological and Clinical Features of Antianginal Drugs.- Nitrites.- Papaverine.- Xanthines.- Khellin.- Recordil.- Monoamineoxydase Inhibitors (Maoi).- Irrigor.- Segontin.- Amplivix.- Isoptin.- Persantine.- Intensaine.- Ustimon.- Ildamen.- Clinium.- ?-Adrenergic Blocking Drugs.- Cordarone.- Miscellaneous.- Section no. 1.- Adenylocrat.- Aminocetone.- Anginin.-Baralgin.- Baxacor.- Eucilat.- Griseofulvine.- Mederel.- Opticardon.- Pexid.- Piridoxilate.- Polarising Solutions.- Sandolanid.- Surheme.- Terodiline.- Tromcardin.- Vastarel.- Vialibran.- Section no. 2.- Morphine.- Barbiturates.- Ethyl Alcohol.- Valium.- Phenothiazines.- Diphenylhydantoin.- Cinchona Alcaloids.- Daucarine.- Vitamin E.- Hexoestrol.- Adenosine and Related Substances.- Thyroxine.- Section no. 3.- Phenoxy-Isopropyl-Norsuprifen.- Phenyl-Isobutyl-Norsuprifen.- Cyclospasmol.- Vasculat.- Reserpine.- Padutin.- Recosen.- Cortunon.- Heparin.- Dicoumarol.- Ilidar.- Priscol.- Hydergine.- Ronicol.- Poly-Methoxyphenol Derivatives.- Triparanol.- Varia.- Carotid Sinus Nerve Stimulation.- Prospects of future research.- Table of Side Effects in Man.- References.- Author Index.