Cantitate/Preț
Produs
Total produse
Vezi coșul
New Approaches to Drug Discovery de Ulrich Nielsch

New Approaches to Drug Discovery: Handbook of Experimental Pharmacology, cartea 232

Editat de Ulrich Nielsch, Ulrike Fuhrmann, Stefan Jaroch
en Limba Engleză Hardback – 8 apr 2016
This volume gives an overview ofstate of the art technologies and future developments in the field ofpreclinical pharmaceutical research. A balanced mix of experts from academiaand industry give insight in selected new developments in the drug discoverypathway. The topics cover the different parts of the drug discovery process,starting with new developments in the target identification and validationarea. The lead generation part as a next step focuses on the requirements andtechnologies to identify new small molecules as lead compounds for furtheroptimization; in a second section the technologies to identify biologics asleads are addressed. The final part focuses on the pharmacological models andtechnologies to characterize new compounds and the impact of biomarkers to facilitatethe transfer of drug candidates into the development phase.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 130060 lei  38-44 zile
  Springer International Publishing – 25 apr 2018 130060 lei  38-44 zile
Hardback (1) 140189 lei  3-5 săpt.
  Springer International Publishing – 8 apr 2016 140189 lei  3-5 săpt.

Din seria Handbook of Experimental Pharmacology

  • 5% Bacterial Protein Toxins
    Preț: 142504 lei
  • 5% Therapeutic Antibodies
    Preț: 90742 lei
  • 5% Adenosine Receptors in Health and Disease
    Preț: 345824 lei
  • 5% Urinary Tract
    Preț: 73030 lei
  • 5% Metabolic Control
    Preț: 141104 lei
  • 5% Adhesion G Protein-coupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease
    Preț: 140637 lei
  • 5% The Actin Cytoskeleton
    Preț: 189804 lei
  • 5% Free Fatty Acid Receptors
    Preț: 188997 lei
  • 5% Pharmacology of Mitochondria
    Preț: 190470 lei
  • 5% Histamine and Histamine Receptors in Health and Disease
    Preț: 208176 lei
  • 5% Pharmacologic Therapy of Ocular Disease
    Preț: 208408 lei
  • 5% Targeting Trafficking in Drug Development
    Preț: 208156 lei
  • 5% New Psychoactive Substances: Pharmacology, Clinical, Forensic and Analytical Toxicology
    Preț: 108815 lei
  • 5% Botulinum Toxin Therapy
    Preț: 107975 lei
  • 5% Organotypic Models in Drug Development
    Preț: 139630 lei
  • 5% Organic Cation Transporters in the Central Nervous System
    Preț: 108619 lei
  • 5% Pharmacology of Immunosuppression
    Preț: 108619 lei
  • 5% Physiology, Pharmacology and Pathology of the Blood-Brain Barrier
    Preț: 108945 lei
  • 5% Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease
    Preț: 108802 lei
  • 5% Sex and Gender Effects in Pharmacology
    Preț: 108712 lei
  • 5% Drug Delivery and Targeting
    Preț: 115453 lei
  • 5% Erzeugung von Krankheitszuständen durch das Experiment: Teil 11A Infektionen III
    Preț: 40165 lei
  • 5% Morphin und Morphinähnlich Wirkende Verbindungen
    Preț: 40275 lei
  • 5% Die Pharmakologie Anorganischer Anionen: Die Hofmeistersche Reihe
    Preț: 53989 lei
  • 5% Targeted Drug Delivery
    Preț: 70834 lei
  • 5% Biochemical Pharmacology of Blood and Bloodforming Organs
    Preț: 72074 lei
  • 5% Physiology and Pharmacology of the Blood-Brain Barrier
    Preț: 71896 lei
  • 5% Opioids I
    Preț: 73386 lei
  • 5% Opioids II
    Preț: 73513 lei
  • 5% Gastrointestinal Regulatory Peptides
    Preț: 71302 lei
  • 5% Physiology and Pharmacology of Bone
    Preț: 73029 lei
  • 5% GTPases in Biology I
    Preț: 38664 lei
  • 5% GTPases in Biology II
    Preț: 72329 lei
  • 5% Principles and Treatment of Lipoprotein Disorders
    Preț: 71607 lei
  • 5% Lobelin und Lobeliaalkaloide
    Preț: 38299 lei
  • 5% Pharmacokinetics of Drugs
    Preț: 71841 lei
  • 5% Pharmacology of Smooth Muscle
    Preț: 72811 lei
  • 5% Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity
    Preț: 71790 lei
  • 5% The Pharmacology of Monoclonal Antibodies
    Preț: 71123 lei
  • 5% The Pharmacology of Alcohol Abuse
    Preț: 71896 lei
  • 5% Toxicology of Metals: Biochemical Aspects
    Preț: 71444 lei
  • 5% The Pharmacology of Sleep
    Preț: 345698 lei
  • 5% Diuretics
    Preț: 71698 lei
  • 5% Pharmacological Aspects of Drug Dependence: Toward an Integrated Neurobehavioral Approach
    Preț: 72470 lei
  • 5% Antipsychotics
    Preț: 71861 lei
  • 5% Drug-Induced Hepatotoxicity
    Preț: 72633 lei
  • 5% Mechanisms of Drug Interactions
    Preț: 89459 lei
  • 5% Glucagon III
    Preț: 70797 lei

Preț: 140189 lei

Preț vechi: 147567 lei
-5% Nou

Puncte Express: 2103
Preț estimativ în valută:
26829€ • 27950$ • 22307£

Carte disponibilă

Livrare economică 20 ianuarie-03 februarie 25

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9783319289120
ISBN-10: 3319289128
Pagini: 370
Ilustrații: VIII, 341 p. 100 illus., 63 illus. in color.
Dimensiuni: 155 x 235 x 23 mm
Greutate: 0.82 kg
Ediția:1st ed. 2016
Editura: Springer International Publishing
Colecția Springer
Seria Handbook of Experimental Pharmacology

Locul publicării:Cham, Switzerland

Public țintă

Research

Cuprins

Preface.-Part 1. Historical View.- Drug discovery in the past and today.Part 2. Target Discovery.- Emerging target families:intractable targets. In vivo target validation especially for biologicaltargets. HR RNAi/High Content analysis.- Part 3. Lead generation and Optimization.- Sources for leads: natural products,libraries. Screening: assays, readout, technology. Impact of structuralbiology, fragment based screening/Virtual screening. Predictive in silico toolsof compound properties. High throughput synthesis. New compound classes:Protein-Protein Interaction. Sources for biological leads/Screening ofbiologicals.- Part 4. Test systems forEfficacy and Safety.- In vitro/ Cell based assays. Pharmacodynamic. Pharmacokinetic. Safety and toxicology. Impactof biomarkers/personalized medicine. Simulating in vivo drug effects.

Notă biografică

Dr. Ulrich Nielsch, Bayer Pharma AG,Wuppertal, Germany
Dr. Ulrike Fuhrmann, Bayer Pharma AG, Berlin, Germany
Prof. Dr. Stefan Jaroch, Bayer Pharma AG, Berlin, Germany

Caracteristici

In depth insights into drug discovery and early drug development Latest technologies of target discovery and lead generation New approaches to transfer drug candidates to clinical development