Cantitate/Preț
Produs
Total produse
Vezi coșul
Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery de Philip J. Rosenthal

Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery: Infectious Disease

Editat de Philip J. Rosenthal
en Limba Engleză Hardback – apr 2001
Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery clearly delineates all the basic and clinical research now addressing one of the world's major unresolved disease problems, work that is now powerfully driving the rapid pace of antimalarial drug discovery today.
Citește tot Restrânge

Toate formatele și edițiile

Toate formatele și edițiile Preț Express
Paperback (1) 107439 lei  6-8 săpt.
  Humana Press Inc. – 19 noi 2010 107439 lei  6-8 săpt.
Hardback (1) 138928 lei  6-8 săpt.
  Humana Press Inc. – apr 2001 138928 lei  6-8 săpt.

Din seria Infectious Disease

  • 5% Infectious Disease in the Aging: A Clinical Handbook
    Preț: 64639 lei
  • 5% National Institute of Allergy and Infectious Diseases, NIH: Volume 3: Intramural Research
    Preț: 139405 lei
  • 18% Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions
    Preț: 70279 lei
  • 5% Opportunistic Infections: Treatment and Prophylaxis
    Preț: 77818 lei
  • 5% Pathogen Genomics: Impact on Human Health
    Preț: 68299 lei
  • 5% Retroviral Immunology: Immune Response and Restoration
    Preț: 107884 lei
  • 5% Infectious Diseases and Arthropods
    Preț: 106284 lei
  • 5% Epidemiological and Molecular Aspects on Cholera
    Preț: 137417 lei
  • 5% Vaccine Adjuvants
    Preț: 106977 lei
  • 5% Management of Multiple Drug-Resistant Infections
    Preț: 76823 lei
  • 5% Innate Immunity
    Preț: 102711 lei
  • 5% Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, Volume 2
    Preț: 136417 lei
  • 18% Molecular Typing in Bacterial Infections
    Preț: 124390 lei
  • 5% National Institute of Allergy and Infectious Diseases, NIH: Volume 1: Frontiers in Research
    Preț: 203853 lei
  • 18% Chemical and Physical Signatures for Microbial Forensics
    Preț: 91787 lei
  • 5% Management of Antimicrobials in Infectious Diseases: Impact of Antibiotic Resistance
    Preț: 137365 lei
  • 5% Infectious Causes of Cancer: Targets for Intervention
    Preț: 108200 lei
  • 5% Reverse Transcriptase Inhibitors in HIV/AIDS Therapy
    Preț: 139068 lei
  • 5% Cytokines and Chemokines in Infectious Diseases Handbook
    Preț: 108950 lei
  • 5% Drug Interactions in Infectious Diseases
    Preț: 108557 lei
  • 5% Immunotherapy for Infectious Diseases
    Preț: 70235 lei
  • 18% Microbial Genomes
    Preț: 121740 lei
  • 5% Foodborne Diseases
    Preț: 132166 lei
  • 5% The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes
    Preț: 138662 lei
  • 5% Congenital and Perinatal Infections
    Preț: 72501 lei
  • 5% Aging, Immunity, and Infection
    Preț: 69220 lei

Preț: 138928 lei

Preț vechi: 146240 lei
-5% Nou

Puncte Express: 2084
Preț estimativ în valută:
26589€ • 28050$ • 22158£

Carte tipărită la comandă

Livrare economică 03-17 ianuarie 25

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9780896036703
ISBN-10: 0896036707
Pagini: 396
Ilustrații: XI, 396 p.
Dimensiuni: 178 x 254 x 24 mm
Greutate: 0.93 kg
Ediția:2001
Editura: Humana Press Inc.
Colecția Humana
Seria Infectious Disease

Locul publicării:Totowa, NJ, United States

Public țintă

Professional/practitioner

Cuprins

I Introduction.- 1 The Need for New Approaches to Antimalarial Chemotherapy.- 2 The History of Antimalarial Drugs.- 3 Transport and Trafficking in Plasmodium-Infected Red Cells.- 4 The Plasmodium Food Vacuole.- 5 Clinical and Public Health Implications of Antimalarial Drug Resistance.- II Established Antimalarial Drugs and Compounds Under Clinical Development.- 6 Chloroquine and Other Quinoline Antimalarials.- 7 8-Aminoquinolines.- 8 Mechanisms of Quinoline Resistance.- 9 Folate Antagonists and Mechanisms of Resistance.- 10 Artemisinin and Its Derivatives.- 11 Atovaquone—Proguanil Combination.- 12 The Antimalarial Drug Portfolio and Research Pipeline.- III New Compounds, New Approaches, and New Targets.- 13 Novel Quinoline Antimalarials.- 14 New Antimalarial Trioxanes and Endoperoxides.- 15 Antibiotics and the Plasmodial Plastid Organelle.- 16 Fresh Paradigms for Curative Antimetabolites.- 17 Iron Chelators.- 18 Protease Inhibitors.- 19 Inhibitors of Phospholipid Metabolism.- 20 Development of New Malaria Chemotherapy by Utilization of Parasite-Induced Transport.

Recenzii

"With contributions from 41 different authors, this book provides a welcome collection of short reviews covering numerous topics in antimalarial chemotherapy. ...this book will offer a useful review for those who study malaria and, more importantly, an entry point into antimalarial chemotherapy for those new in the field." - Journal of Medicinal Chemistry

"...the publication of a new on antimalarial chemotheraphy is very topcial and timely. Philip Rosenthal has put together a very comprehensive book on the current status of research in this important field of medicianl chemistry....The part on established antimalarial drugs covers all drugs currently in clinical application and trials....Special emphasis is put in many articles on aspects of toxicity, therapy, problems, and future developments....the editor has managed to compile the contributions in such a way that a comprehensive picture of the current status emerges and the book feels more like a single-author publication than an edited work....The book is a must for chemists, biologists, and health professionals involved in malaria research." - ChemBioChem

"...thought provoking with its new leads to drug discovery...an essential addition to the libraries and an essential reading book for malariologists." -The National Journal of India

Textul de pe ultima copertă

At a time when the control of malaria is increasingly limited by the growing resistance of malaria parasites to available drugs, the need for a much better use of the existing drugs, as well as for the development of new antimalarials, has become urgent. In Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery, a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. The survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, and new chemical approaches to and possible new targets for chemotherapy. It also discusses, as essential background, the history of chemotherapy, the practical aspects of therapy, and the public health consequences of current problems in antimalarial chemotherapy.
Comprehensive and cutting-edge, Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery clearly delineates all the basic and clinical research now addressing one of the world's major unresolved disease problems, work that is now powerfully driving the rapid pace of antimalarial drug discovery today.

Caracteristici

Includes supplementary material: sn.pub/extras