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Biometals & Ligands for Anticancer Drug Design: Molecular Mechanisms of Superoxide Dismutase Models Antitumor Effects

Autor E A Parfenov, G. E. Zaikov
en Limba Engleză Hardback – 11 dec 1998
Biometals & Ligands for Anticancer Drug Design - Molecular Mechanisms of Superoxide Dismutase Models Antitumor Effects
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Specificații

ISBN-13: 9781560725428
ISBN-10: 1560725427
Pagini: 380
Ilustrații: d.tabs.
Dimensiuni: 240 x 160 x 28 mm
Greutate: 0.7 kg
Editura: Nova Science Publishers Inc
Colecția Nova Science Publishers, Inc (US)

Cuprins

Contents: Introduction; The Search for Antitumour Agents Among Complex Copper Compounds; SOD Models as Anticarcinogens; Resemblance and Differences of SOD Models and Enzymes. Probable Functions of SOD Models in Biological Systems; Cytotoxic Activity of SOD Models; Mechanisms of Physiological Compatibility of SOD Models 1 -- The Role of Ligand Selection for the SOD Model Design; Mechanisms of Physiological Compatibility of SOD Models 2 -- Effects in the Cell Redox Potential; Mechanisms of Physiological Compatibility of SOD Models 3 -- Interaction with the Immune System; Mechanisms of Physiological Compatibility of SOD Models 4 -- Gene Expression; Mechanisms of Physiological Compatibility of SOD Models 5 -- Overcoming of the Drug Resistance; If a Universal Antioxidant is Possible.