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Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications de Claudiu T. Supuran

Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications

Editat de Claudiu T. Supuran, Giuseppina De Simone
en Limba Engleză Hardback – 8 ian 2015
Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. The Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents information on the growing interest in the study of this enzyme family and their applications to both medicine and biotechnology.


  • Offers comprehensive coverage of the carbonic anhydrases enzyme family and their properties as biocatalysts
  • Includes current applications of carbonic anhydrases in biotechnology on the basis of their catalytic efficiency, including new technologies for CO2 capture processes
  • Identifies new targets for drug design studies
  • Provides a selectivity profile for the different carbonic anhydrases and their related biomedical applications
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Specificații

ISBN-13: 9780444632586
ISBN-10: 0444632581
Pagini: 398
Ilustrații: 50 illustrations
Dimensiuni: 191 x 235 x 22 mm
Greutate: 0.89 kg
Editura: ELSEVIER SCIENCE

Public țintă

It can be useful for many type of readers: biochemists, chemists and specialists in drug design, but also medical doctors and for students of life sciences.

Cuprins

Preface
PART I INTRODUCTION
1. Carbonic Anhydrases: an overview
PART II CARBONIC ANHYDRASES AS DRUG TARGETS
2. Human Carbonic Anhydrases: catalytic properties, structural features and tissue distribution
3. Carbonic Anhydrase I
4. Carbonic Anhydrase II as target from drug design
5. Carbonic Anhydrase III
6. Carbonic Anhydrase IV
7. The structure, physiological role and potential medicinal applications of Carbonic Anhydrase V
8. Secreted Carbonic Anhydrase Isoenzyme VI
9. Carbonic Anhydrase VII
10. Tumor associated carbonic Anhydrases IX and XII
11. Carbonic anhydrase XIII
12. Carbonic anhydrase XIV: structure, functions and potential medical applications
13. Acatalytic Carbonic anhydrases (CAs VIII, X, XI)
14. Beta-class Carbonic anhydrases: general features and medical implications
15. Bacterial Carbonic Anhydrases as drug targets
PART III CARBONIC ANHYDRASES FOR BIOTECHNOLOGICAL APPLICATIONS
16. Engineered mammalian Carbonic Anhydrases for CO2 capture
17. Carbonic anhydrases from extremophiles and their biotechnological applications
18. Carbonic Anhydrases of environmentally and medically relevant anaerobic prokaryotes
19. Delta Carbonic anhydrases: structure, distribution and potential roles
20. CDCA1 from Thalassiosira weissflogii as representative member of zeta-class CAs: general features and biotechnological applications of anhydrases
21. Carbonic anhydrases as esterases and their biotechnological applications