Chromogranins: from Cell Biology to Physiology and Biomedicine: UNIPA Springer Series
Editat de Tommaso Angelone, Maria Carmela Cerra, Bruno Totaen Limba Engleză Paperback – 5 sep 2018
The volume is of interest for laboratory and clinical scientists, PhD and Post-doc students that will be inspired to go deep inside the molecular, biochemical, physiological, pharmacological and clinical aspects of these fascinating multifaceted proteins.
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Toate formatele și edițiile | Preț | Express |
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Paperback (1) | 663.15 lei 38-44 zile | |
Springer International Publishing – 5 sep 2018 | 663.15 lei 38-44 zile | |
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Specificații
ISBN-13: 9783319863818
ISBN-10: 3319863819
Pagini: 267
Ilustrații: IX, 267 p. 16 illus., 4 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:Softcover reprint of the original 1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Seria UNIPA Springer Series
Locul publicării:Cham, Switzerland
ISBN-10: 3319863819
Pagini: 267
Ilustrații: IX, 267 p. 16 illus., 4 illus. in color.
Dimensiuni: 155 x 235 mm
Ediția:Softcover reprint of the original 1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Seria UNIPA Springer Series
Locul publicării:Cham, Switzerland
Cuprins
Chromaffin cells and Granins: History and Perspectives.- The extended granin family: structure, function, and biomedical implications.- CgA and CgB in granule secretion.- Proteolytic processing of CgA and CgB/Antimicrobial properties of Chromogranins.- Chromogranins and inositol 1,4,5-trisphosphate-dependent Ca2+-signaling.- CgA in angiogenesis and tumor biology.- Full lenght CgA: a multifaceted protein in cardiovascular health and disease.- Physio-pharmacological aspects of three Chromogranin A-derived peptides: Vasostatin, Catestatin, and Serpinin.- Comparative aspects of CgA-derived peptides in cardiac homeostasis.- Molecular and cellular mechanisms of action of CgA-derived peptides in cardiomyocytes and endothelial cells.- CgA-derived peptides in pre- and post-conditioning cardioprotection.- Catestatin in physiopathology.- Serpinin: from biosynthesis to cell biology and physiopathology.- Pancreastatin and metabolism.- Chromogranins and the quantum release of catecholamines.
Textul de pe ultima copertă
The volume is designed to provide an integrated overview of the results from the last fifteen years of research on Chromogranins in relation to cell biology, physiology and biomedicine. The different chapters highlight novel activities of these proteins, including their role in granule biogenesis, hormone co-storage, stimulus-processing-secretion coupling, autonomic sympathetic/parasympathetic balance, immune and cardiocirculatory function, and the response to stress. Biomedical aspects are also illustrated with focus on the prognostic and diagnostic significance of Chromogranin in the presence of tumors, cardiovascular diseases and inflammatory conditions.
The volume is of interest for laboratory and clinical scientists, PhD and Post-doc students that will be inspired to go deep inside the molecular, biochemical, physiological, pharmacological and clinical aspects of these fascinating multifaceted proteins.
Caracteristici
Updates the state-of-the art information on chromogranins for researchers, PhD students and Post-docs Provides an integrated analysis of chromogranins biological significance in health and disease Highlights the prognostic and diagnostic potential of chromogranins