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The Hair Fibre: Proteins, Structure and Development: Advances in Experimental Medicine and Biology, cartea 1054

Editat de Jeffrey E. Plowman, Duane P. Harland, Santanu Deb-Choudhury
en Limba Engleză Hardback – 8 iun 2018
Hair is a sophisticated bio-based material, whether it is on a human head or part of a mammalian coat. In particular, the role of the proteins in the follicle, integral to hair development, are not well understood. This new book seeks to integrate the latest research in proteomic and morphological studies into a coherent description of fibre development from the follicle to its final mature, keratinized form.
To achieve this the book has been divided into three sections.  The first describes the keratins, their associated proteins and how they assemble into intermediate filaments in the fibre. The second covers the latest information on the morphological changes that occur from the base of the follicle, through the keratinization process to the mature fibre and the role that proteins play in this. The final section delves into fundamental fibre properties such as crosslinking, thermal and oxidative modifications and how these affect the mature fibre. The editors of this book are internationally recognised for their work in the area of mammalian hair, Jeffrey Plowman for his knowledge of the proteomics of the fibre, Santanu Deb-Choudhury for his work in the area of crosslinking in the fibre and Duane Harland for his understanding of the morphological development of the fibre. Together they have collected material from other international experts: Leopold Eckhart and Florian Ehrlich for their knowledge of the evolution of keratins; Dong Dong Wu and David Irwin for their studies on keratin associated protein evolution; David Parry and Bruce Fraser for their work on keratin and keratin associated protein structure and assembly; John McKinnon for his studies on macrofibril formation; Crisan Popescu for the thermodynamics of keratins; and Jolon Dyer for his oxidative modification studies of keratins.
This book provides a comprehensive introduction, and useful reference guide to hair biology and will be of interest to both scientists and technologists.
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Specificații

ISBN-13: 9789811081941
ISBN-10: 9811081948
Pagini: 231
Ilustrații: VIII, 225 p. 76 illus., 42 illus. in color.
Dimensiuni: 178 x 254 x 14 mm
Greutate: 0.64 kg
Ediția:1st ed. 2018
Editura: Springer Nature Singapore
Colecția Springer
Seria Advances in Experimental Medicine and Biology

Locul publicării:Singapore, Singapore

Cuprins

  1. Introduction to Hair and Follicles

    1. Front Matter

      Pages 1-1

      PDF

    2. Fibre Ultrastructure

      Jeffrey E. Plowman, Duane P. Harland

      Pages 3-13

    3. The Follicle Cycle in Brief

      Jeffrey E. Plowman, Duane P. Harland

      Pages 15-17

  2. Hair Proteins

    1. Front Matter

      Pages 19-19

      PDF

    2. Diversity of Trichocyte Keratins and Keratin Associated Proteins

      Jeffrey E. Plowman

      Pages 21-32

    3. Evolution of Trichocyte Keratins

      Leopold Eckhart, Florian Ehrlich

      Pages 33-45

    4. Evolution of Trichocyte Keratin Associated Proteins

      Dong-Dong Wu, David M. Irwin

      Pages 47-56

    5. Structural Hierarchy of Trichocyte Keratin Intermediate Filaments

      R. D. Bruce Fraser, David A. D. Parry

      Pages 57-70

    6. Trichocyte Keratin-Associated Proteins (KAPs)

      R. D. Bruce Fraser, David A. D. Parry

      Pages 71-86

  3. Hair Development

    1. Front Matter

      Pages 87-87

      PDF

    2. Introduction to Hair Development

      Duane P. Harland

      Pages 89-96

    3. Environment of the Anagen Follicle

      Duane P. Harland

      Pages 97-108

    4. Development of Hair Fibres

      Duane P. Harland, Jeffrey E. Plowman

      Pages 109-154

    5. Macrofibril Formation

      Duane P. Harland, A. John McKinnon

      Pages 155-169

  4. Hair Chemistry and Thermodynamics

    1. Front Matter

      Pages 171-171

      PDF

    2. Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins

      Santanu Deb-Choudhury

      Pages 173-183

    3. The Thermodynamics of Trichocyte Keratins

      Crisan Popescu

      Pages 185-203

    4. Oxidative Modification of Trichocyte Keratins

      Jolon M. Dyer

      Pages 205-218

  5. Back Matter

    Pages 219-225


Textul de pe ultima copertă

Hair is a sophisticated bio-based material, whether it is on a human head or part of a mammalian coat. In particular, the role of the proteins in the follicle, integral to hair development, are not well understood. This new book seeks to integrate the latest research in proteomic and morphological studies into a coherent description of fibre development from the follicle to its final mature, keratinized form.
To achieve this the book has been divided into three sections.  The first describes the keratins, their associated proteins and how they assemble into intermediate filaments in the fibre. The second covers the latest information on the morphological changes that occur from the base of the follicle, through the keratinization process to the mature fibre and the role that proteins play in this. The final section delves into fundamental fibre properties such as crosslinking, thermal and oxidative modifications and how these affect the mature fibre. The editors of this book are internationally recognised for their work in the area of mammalian hair, Jeffrey Plowman for his knowledge of the proteomics of the fibre, Santanu Deb-Choudhury for his work in the area of crosslinking in the fibre and Duane Harland for his understanding of the morphological development of the fibre. Together they have collected material from other international experts: Leopold Eckhart and Florian Ehrlich for their knowledge of the evolution of keratins; Dong Dong Wu and David Irwin for their studies on keratin associated protein evolution; David Parry and Bruce Fraser for their work on keratin and keratin associated protein structure and assembly; John McKinnon for his studies on macrofibril formation; Crisan Popescu for the thermodynamics of keratins; and Jolon Dyer for his oxidative modification studies of keratins.
This book provides a comprehensive introduction, and useful reference guide to hair biology and will be of interest to both scientists and technologists.


Caracteristici

Is the first book that brings together decades of research on keratin biochemistry and fibre
Fills a gap in the market for a research book in the scientific, cosmetic and medical areas
Has contributions from globally recognized experts in their field

Descriere

Hair is a sophisticated bio-based material, whether it is on a human head or part of a mammalian coat. In particular, the role of the proteins in the follicle, integral to hair development, are not well understood. This new book seeks to integrate the latest research in proteomic and morphological studies into a coherent description of fibre development from the follicle to its final mature, keratinized form.
To achieve this the book has been divided into three sections.  The first describes the keratins, their associated proteins and how they assemble into intermediate filaments in the fibre. The second covers the latest information on the morphological changes that occur from the base of the follicle, through the keratinization process to the mature fibre and the role that proteins play in this. The final section delves into fundamental fibre properties such as crosslinking, thermal and oxidative modifications and how these affect the mature fibre. The editors of this book are internationally recognised for their work in the area of mammalian hair, Jeffrey Plowman for his knowledge of the proteomics of the fibre, Santanu Deb-Choudhury for his work in the area of crosslinking in the fibre and Duane Harland for his understanding of the morphological development of the fibre. Together they have collected material from other international experts: Leopold Eckhart and Florian Ehrlich for their knowledge of the evolution of keratins; Dong Dong Wu and David Irwin for their studies on keratin associated protein evolution; David Parry and Bruce Fraser for their work on keratin and keratin associated protein structure and assembly; John McKinnon for his studies on macrofibril formation; Crisan Popescu for the thermodynamics of keratins; and Jolon Dyer for his oxidative modification studies of keratins.
This book provides a comprehensive introduction, and useful reference guide to hair biology and will be of interest to both scientists and technologists.