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Colloids in Drug Delivery: Surfactant Science

Editat de Monzer Fanun
en Limba Engleză Paperback – 16 noi 2016
Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles the work of 65 of the world’s leading colloid scientists who examine the full spectrum of this rapidly emerging science, from pure to applied, most of it drawn from their own experience and research.
The book begins by examining the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds, and their use in drug delivery and biotechnology. It examines the development of controlled and targeted delivery systems by utilizing the various properties of colloids before moving on to discuss various applications and fields of research.
Topics discussed include:
  • The use of hard, soft, and macromolecular colloidal drug delivery systems formed by surfactants, polymers, proteins, and lipids
  • Recent advances in procolloidal systems, self-emulsifying drug delivery systems, and aerosol applications to pharmaceutical drug delivery
  • Colloidal nanocarriers for imaging applications and the treatment of dental and periodontal diseases
  • Classification and application of colloidal drug delivery systems in tumor targeting
  • The use of colloids for improved nasal, ocular, vaginal, oral, buccal, gastrointestinal, and colon drug delivery
Examining topics necessary to the critical evaluation of a drug candidate’s potential for delivery, the book also describes the preparation, classification, interfacial activity, surface modifications and influence on particle characteristics, drug delivery, and drug targeting. Each chapter in this expansive volume explains why a particular system is used for the intended application, how it is made, and how it behaves.
All those concerned with the research, development, and manufacture of drugs will find this a valuable reference, offering a wealth of research upon which they can build.
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Specificații

ISBN-13: 9781138199156
ISBN-10: 113819915X
Pagini: 652
Ilustrații: 179
Dimensiuni: 178 x 254 mm
Greutate: 0.45 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Surfactant Science


Cuprins

Surfactants and Block Copolymers in Drug Delivery. Application of Colloidal Properties in Drug Delivery.Polymeric Nanocapsules for Drug Delivery: An Overview. Poly(Alkyl Cyanoacrylate) Nanoparticles for Drug Delivery and Vaccine Development. Stimuli-Sensitive Polymer Gels for Dermal and Transdermal Drug Delivery and Their Application in the Development of Smart Textile Materials. Micelles: The Multifunctional Nanocarrier for Colloidal Drug Delivery. Multiple Emulsions: An Overview and Pharmaceutical Applications. Pharmaceutical and Biotechnological Applications of Multiple Emulsions. Nanoemulsions as Drug Delivery Systems. Microemulsion Systems: Application in Delivery of Poorly Soluble Drugs. Diclofenac Solubilization in Mixed Nonionic Surfactants Microemulsions. Self-Emulsifying Drug Delivery Systems. Liquid Crystals and Their Application in the Field of Drug Delivery. Liquid Crystalline Nanoparticles as Drug Nanocarriers. Niosomal Delivery System for Macromolecular Drugs. A New Class of Mesoscopic Aggregates as a Novel Drug Delivery System. Liposomes and Biomacromolecules: Effects of Preparation Protocol on In Vitro Activity. Colloidal Nanocarrier Systems as a Tool for Improving Antimycobacterial and Antitumor Activities and Reducing the Toxicity of Usnic Acid. Dendrimers in Drug Delivery. Microsphere: A Novel Drug Delivery System. Colloids in Aerosol Drug Delivery Systems. Respiratory Aerosol Dynamics with Applications to Pharmaceutical Drug Delivery. Colloidal Carriers for Drug Delivery in Dental Tissue Engineering. Classification and Application of Colloidal Drug Delivery Systems: Passive or Active Tumor Targeting. Nanocarriers for Imaging Applications. Index.

Notă biografică

Monzer Fanun is a member of the faculty of Science and Technology at Al-Quds University.

Descriere

With significant applications in drug delivery and formulation science, colloids offer the same advantages of typical materials used for release but can be tailored to specific bulk material properties such as release profiles. Colloidal systems have the potential to increase the shelf life and improve efficacy of a drug, thus reducing the required dosage concentrations and the frequency of administration. Featuring contributions from an international panel of scientists and researchers, this book presents the most recent findings on the application of colloidal properties in drug delivery systems, contributing to the understanding and improved design of novel and advanced drug delivery applications.