Comprehensive Enzyme Kinetics
Autor Vladimir Leskovacen Limba Engleză Hardback – 31 mar 2003
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Specificații
ISBN-13: 9780306467127
ISBN-10: 0306467127
Pagini: 438
Ilustrații: XII, 438 p.
Dimensiuni: 156 x 234 x 30 mm
Greutate: 0.77 kg
Ediția:2003
Editura: Springer Us
Colecția Springer
Locul publicării:New York, NY, United States
ISBN-10: 0306467127
Pagini: 438
Ilustrații: XII, 438 p.
Dimensiuni: 156 x 234 x 30 mm
Greutate: 0.77 kg
Ediția:2003
Editura: Springer Us
Colecția Springer
Locul publicării:New York, NY, United States
Public țintă
ResearchCuprins
Chemical Kinetics.- Kinetics of Monosubstrate Reactions.- Derivation of Rate Equations.- Linear Inhibition.- Hyperbolic and Parabolic Inhibition.- Enzyme Activation.- Kinetics of Rapid Equilibrium Bisubstrate Reactions.- Steady-State Kinetics of Bisubstrate Reactions.- Kinetic Analysis of Bisubstrate Mechanisms.- Substrate Inhibition and Mixed Dead-End and Product Inhibition.- Trisubstrate Mechanisms.- Cooperative and Allosteric Effects.- The pH Dependence of Enzyme Catalysis.- Effects of Temperature on Enzyme Reactions.- Isotope Exchange.- Kinetic Isotope Effects.- Statistical Analysis of Initial Rate and Binding Data.
Recenzii
`As scientific attention turns in the post-genomic era, once again, to the properties of proteins, and particularly to their preeminent role as catalysts, Professor Leskovac's book, Comprehensive Enzyme Kinetics, will have to be on every shelf. It will, however, rarely find itself on the shelf, but much more in the hands of researchers who will daily deploy in the laboratory its wealth of useful information. Prepared under the eye of W.W. Cleland, the demiurge of enzyme kinetics, this magnum opus earns its title of comprehensive. The systematic organization of the volume, which somehow manages completeness in just over 400 pages, leads the reader to a target subject easily. The clarity of exposition will be as welcome to the experienced kineticist as it will be to the beginner. This volume is a singular achievement.'
R.L. Schowen, Professor Emeritus Chemistry, Molecular Biosciences and Pharmaceutical Chemistry, University of Kansas
`Comprehensive Enzyme Kinetics is an excellent addition to the enzyme kinetics literature. It touches on all of the topics in the various areas of kinetics that might be of interest to the enzymologist. It will make a fine classroom reference text.'
Herbert J. Fromm, Distinguished Professor, Iowa State University
R.L. Schowen, Professor Emeritus Chemistry, Molecular Biosciences and Pharmaceutical Chemistry, University of Kansas
`Comprehensive Enzyme Kinetics is an excellent addition to the enzyme kinetics literature. It touches on all of the topics in the various areas of kinetics that might be of interest to the enzymologist. It will make a fine classroom reference text.'
Herbert J. Fromm, Distinguished Professor, Iowa State University
Caracteristici
Provides a systematic introduction to the field of enzyme-catalyzed reactions Outlines the subject in such a way that it builds from less complicated to more demanding kinetic models