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Concepts and Principles of Pharmacology: 100 Years of the Handbook of Experimental Pharmacology de James E. Barrett

Concepts and Principles of Pharmacology: 100 Years of the Handbook of Experimental Pharmacology: Handbook of Experimental Pharmacology, cartea 260

Editat de James E. Barrett, Clive P. Page, Martin C. Michel
en Limba Engleză Hardback – 17 ian 2020
Celebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
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Specificații

ISBN-13: 9783030353612
ISBN-10: 3030353613
Pagini: 466
Ilustrații: VIII, 466 p. 100 illus., 30 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.84 kg
Ediția:1st ed. 2019
Editura: Springer International Publishing
Colecția Springer
Seria Handbook of Experimental Pharmacology

Locul publicării:Cham, Switzerland

Cuprins

Part 1. A Century of Advances in Pharmacology.- 1. Perspectives of Pharmacology Over the Past 100 years.- 2. Emergent concepts of receptor pharmacology.- 3. The Evolving Landscape of Cancer Therapeutics.- 4. Monoclonal Antibodies: Past, Present and Future.- 5. 100 years of Drug Delivery to the Lungs.- 6. Exploiting the Diversity of Ion Channels:  Ion channel Pharmacology for Pain modulation.- 7. Exploiting the Diversity of Ion Channels:  Modulation of Ion Channels for Therapeutic Indications.- Part 2. Recent developments and enabling technologies in pharmacology.- 8. Genetically Encoded Fluorescent Calcium and Voltage Indicators.- 9. Mechanistic Image-Based Modeling: Concepts and Applications of Image-Based Modeling.- 10. Pharmacometabonomics: The Prediction of Drug Effects Using Metabolic Profiling.- 11. The Microbiome and its Potential for Pharmacology.- 12. Harnessing Human Microphysiology Systems as Key Experimental Models for Quantitative Systems Pharmacology.- Part 3. The future of pharmacology.- 13. The future of clinical trial design: The Transition from Hard Endpoints to Value-Based Endpoings.- 14. Placebos and the Placebo Effect in Drug Trials.- 15. Pharmacoepidemiology.- 16. Why are new drugs expensive and how can they stay affordable?  

Caracteristici

Broadens the understanding of past and present pharmacology as basis of future treatments Reinforces basic principles of pharmacology as the foundation of modern drug discovery Enriches understanding of the history of pharmacology