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Copper in N-Heterocyclic Chemistry

Editat de Ananya Srivastava
en Limba Engleză Paperback – 16 noi 2020
Copper in N-Heterocyclic Chemistry provides an overview of copper-catalyzed synthesis and functionalization of N-heterocyclic compounds, covering all recent developments in a way that is ideal for researchers and students working in the area of synthetic organic chemistry and medicinal chemistry. The book explores N-heterocyclic compounds as unique structural units in the development of natural products and pharmaceuticals, along with the remarkable progress made in the area of high atom economic strategies, and more recently, copper-catalyzed C-H activation and its applications in organic synthesis. Readers will find troubleshooting protocols, as well as the advantages and limitations of each method discussed.
As copper catalysts show versatile chemical reactivity in many aspects, including their oxidation states 0–3 are accessible and their ability to facilitate bond formations due to their ability to serve as Lewis acids, oxidizing agents and catalysts, this book is an ideal resource on the topics explored.


  • Discusses novel synthetic methods developed over the past decade for copper-catalyzed synthesis of N-heterocyclic compounds
  • Covers the most recent methodologies adapted in synthetic chemistry for applications in natural products and pharmaceuticals
  • Includes troubleshooting protocols, as well as the advantages and limitations of each method discussed in detail
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Specificații

ISBN-13: 9780128212639
ISBN-10: 0128212632
Pagini: 504
Ilustrații: Approx. 150 illustrations
Dimensiuni: 152 x 229 x 29 mm
Greutate: 0.67 kg
Editura: ELSEVIER SCIENCE

Cuprins

1. Copper-Catalyzed Synthesis of Aziridines 2. Copper Catalysis for Imidazoles and Pyrazoles 3. Copper catalysis for Triazoles and Tetrazoles 4. Copper Catalysis for Pyridines and Pyrimidines 5. Copper Catalysis for Triazines 6. Copper Catalysis for Pyrazines and Quinoxalines 7. Copper catalysis for Quinolines and Isoquinolines 8. Copper-Mediated Synthesis of Quinazolines and Related Benzodiazines 9. Copper Catalysis for Large Rings 10. Copper Catalysis for Saturated N-Heterocycles via C-H Functionalization 11. Pursuit for Simple and Efficient Ligands Promoting Copper-Catalyzed Type Ullmann Reactions for N-aryl heterocycles and Aromatic Amines 12. Solid Supported Copper for N-heterocycles 13. Copper Catalysis for Biologically Active N-heterocycles