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Diastolic Relaxation of the Heart: Basic Research and Current Applications for Clinical Cardiology de William Grossman

Diastolic Relaxation of the Heart: Basic Research and Current Applications for Clinical Cardiology

Editat de William Grossman, Beverly H. Lorell
en Limba Engleză Paperback – 18 mai 2012
Numerous studies have documented the importance of diastolic dysfunction in heart disease. Now, providing cardiologists with the most current information available on the subject, the editors have pulled together contributions from an impressive array of top researchers and compiled them into one comprehensive, carefully edited source, Diastolic Relaxation of the Heart, Second Edition: The Biology of Diastole in Health and Disease.
This brand new Second Edition, based on a recent meeting, includes such topics as:
  • molecular biology of relaxation;
  • consequences of altered gene expression;
  • impaired relaxation in experimental models (ischemia and hypoxia, and hypertrophy and failure);
  • diastolic dysfunction in the diseased human heart.
Diastolic Relaxation of the Heart, Second Edition: The Biology of Diastole in Health and Disease, the successor to the editors' bestselling work on the same subject, published in 1987 - belongs on the shelf of every practising cardiologist. It will also be an invaluable addition to the library of scientists researching the effects of diastole on heart function.
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Specificații

ISBN-13: 9781461568346
ISBN-10: 146156834X
Pagini: 324
Ilustrații: X, 320 p. 81 illus.
Dimensiuni: 178 x 254 x 23 mm
Greutate: 0.56 kg
Ediția:1988
Editura: Springer Us
Colecția Springer
Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

I: Cell Biology of Diastole.- 1. Cellular Mechanisms of Relaxation: Lessons From Frogs, Birds, and Mammals.- 2. Sarcoplasmic Reticular Control of Cardiac Contraction and Relaxation.- 3. Calcium and Cardiac Relaxation.- 4. Variable Calcium Sensitivity of the Mammalian Cardiac Contractile System.- 5. Is Ischemic Contracture Preceded by a Rise in Free Calcium?.- 6. The Effect of Regional Myocardial Heterogeneity on the Economy of Isometric Relaxation.- 7. Functional Sequelae of Diastolic Sarcoplasmic Reticulum Ca2+ Release in the Myocardium.- II: Physiologic Modifiers of Relaxation in Experimental Models.- 8. Hypoxia and Relaxation.- 9. Ischemic/Hypoxic and Reperfusion/Reoxygenation Contractures: Mechanisms.- 10. Load Dependence of Relaxation.- 11. The Effects of Cardiac Hypertrophy on Intracellular Ca2+ Handling.- III: Evaluation of Relaxation and Compliance in the Intact Heart.- 12. Diastolic Myocardial Mechanics and the Regulation of Cardiac Performance.- 13. Evaluation of Time Course of Left Ventricular Isovolumic Relaxation in Man.- 14. Loading Conditions and Left Ventricular Relaxation.- 15. Influence of Pressure and Volume Overload on Diastolic Compliance.- 16. Influence of the Pericardium on Diastolic Compliance.- 17. Implications of Pericardial Pressure for the Evaluation of Diastolic Dysfunction.- 18. Comparative Effects of Ischemia and Hypoxia on Ventricular Relaxation in Isolated Perfused Hearts.- 19. Effects of Hypoxia on Relaxation of the Hypertrophied Ventricle.- 20. Relaxation and Diastolic Distensibility of the Regionally Ischemic Left Ventricle.- IV: Clinical Disorders of Diastolic Relaxation and Compliance.- 21. Altered Diastolic Distensibility During Angina Pectoris.- 22. Diastolic Function During Exercise-Induced Ischemia in Man.- 23. Left VentricularFilling in Ischemic and Hypertrophic Heart Disease.- 24. Regional Diastolic Dysfunction in Coronary Artery Disease: Clinical and Therapeutic Implications.- 25. Ejection, Filling, and Diastasis During Transluminal Occlusion in Man: Consideration on Global and Regional Left Ventricular Function.- 26. Diastolic Ventricular Function in Primary and Secondary Hypertrophy: The Influence of Verapamil.- 27. Failure of Inactivation of Hypertrophied Myocardium: A Cause of Impaired Left Ventricular Filling in Hypertrophic Cardiomyopathy and Aortic Stenosis.

Descriere

Descriere de la o altă ediție sau format:
Numerous studies have documented the importance of diastolic dysfunction in heart disease. Now, providing cardiologists with the most current information available on the subject, the editors have pulled together contributions from an impressive array of top researchers and compiled them into one comprehensive, carefully edited source, Diastolic Relaxation of the Heart, Second Edition: The Biology of Diastole in Health and Disease.
This brand new Second Edition, based on a recent meeting, includes such topics as:
  • molecular biology of relaxation;
  • consequences of altered gene expression;
  • impaired relaxation in experimental models (ischemia and hypoxia, and hypertrophy and failure);
  • diastolic dysfunction in the diseased human heart.
Diastolic Relaxation of the Heart, Second Edition: The Biology of Diastole in Health and Disease, the successor to the editors' bestselling work on the same subject, published in 1987 - belongs on the shelf of every practising cardiologist. It will also be an invaluable addition to the library of scientists researching the effects of diastole on heart function.