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Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships

Autor Brian A. Baldo, Nghia H. Pham
en Limba Engleză Paperback – 23 mai 2016
The variety of chemically diverse pharmacological agents administered to patients is large and continues to expand and with every new drug released, there is always potential for adverse reactions, some of them allergic. With its roots in immunology and pharmacology, the science of drug allergy is becoming better understood and applied as its importance is increasingly recognized throughout the many branches of medicine.   Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships sheds new light on this field. Comprehensive in design, this authoritative title identifies the most important culprit drugs implicated in immediate and delayed drug hypersensitivities and offers up-to-date information on classifications, diagnoses, underlying mechanisms and structure-activity relationships.  Chapters dealing with the molecular and cellular mechanisms of drug hypersensitivities, non-immune-mediated sensitivities and diagnostic methods are presented as introductory material for in-depth treatises on the β-lactam antibiotics, other antibiotics and antimicrobials, drugs used in anesthesia and surgery, opioid analgesics, corticosteroids, monoclonal antibodies and other biologics, drugs used in chemotherapy, proton pump inhibitors, iodinated and gadolinium-based contrast media and non-steroidal anti-inflammatory drugs.  In addition to being of immense value to clinicians, other health care professionals and researchers, this title will prove invaluable for those taking undergraduate and graduate courses in science and will also serve as a useful text for students of medicine, pharmacy, nursing and dentistry.
 
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Specificații

ISBN-13: 9781493963904
ISBN-10: 1493963902
Pagini: 447
Ilustrații: XVIII, 447 p. 228 illus., 70 illus. in color.
Dimensiuni: 178 x 254 x 25 mm
Greutate: 1.13 kg
Ediția:1st ed. 2013
Editura: Springer
Colecția Springer
Locul publicării:New York, NY, United States

Cuprins

 
Preface
Chapter 1       Adverse Reactions to Drugs and Drug Allergy: Scope of this Book
Chapter 2       Classification and Descriptions of Allergic Reactions to Drugs
Chapter 3       Mechanisms of Hypersensitivity
Chapter 4       Diagnosis of Allergic Reactions to Drugs
Chapter 5       β-Lactam Antibiotics
Chapter 6       Other Antimicrobial Drugs
Chapter 7       Drugs and Other Agents Used in Anesthesia and Surgery
Chapter 8       Opioid Analgesic Drugs
Chapter 9       Non-Steroidal Anti-Inflammatory Drugs
Chapter 10     Contrast Media
Chapter 11     Biologics
Chapter 12     Corticosteroids
Chapter 13     Drugs Used for Chemotherapy
Chapter 14     Proton Pump Inhibitors
Postface

Recenzii

From the reviews:
“The current book offers valuable knowledge regarding mechanisms, clinical aspects, diagnostic methods, and therapeutic approach in drug allergy, which will aid the caring physician to successfully diagnose and manage affected individuals. … The summary points at the end of each chapter represent an outstanding feature of this book. As a comprehensive overview of the mechanisms, clinical manifestations and diagnostic methods in drug allergy will provide valuable and practical information for every physician interested in this disease.” (Juan Carlos Aldave, World Allergy Organization, worldallergy.org, February, 2014)
“Book presents the science behind what truly is an allergic reaction to guide evidence-based decisions on drug therapy. It addresses the clinical aspects of allergy in addition to the mechanism of disease, the molecular chemistry behind allergy, and other key features. … Although this can be a valuable reference for anyone in healthcare, the primary audience is composed of physicians, pharmacists, and nurses, as well as students … . a great reference for those who wish more information or are preparing lectures on this topic.” (Patrick J. McDonnell, Doody’s Book Reviews, October, 2013)

Notă biografică

Dr. Brian A. Baldo

Dr. Nghia H. Pham

Textul de pe ultima copertă

The variety of chemically diverse pharmacological agents administered to patients is large and continues to expand and with every new drug released, there is always potential for adverse reactions, some of them allergic. With its roots in immunology and pharmacology, the science of drug allergy is becoming better understood and applied as its importance is increasingly recognized throughout the many branches of medicine.  Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships sheds new light on this field. Comprehensive in design, this authoritative title identifies the most important culprit drugs implicated in immediate and delayed drug hypersensitivities and offers up-to-date information on classifications, the many different drug-induced systemic and cutaneous reactions, diagnoses, underlying mechanisms and structure-activity relationships.  Chapters dealing with the molecular and cellular mechanisms of drug hypersensitivities, non-immune-mediated sensitivities and diagnostic methods are presented as introductory material for in-depth treatises on the β-lactam antibiotics, other antibiotics and antimicrobials, drugs used in anesthesia and surgery, opioid analgesics, corticosteroids, monoclonal antibodies and other biologics, drugs used in chemotherapy, proton pump inhibitors, iodinated and gadolinium-based contrast media and non-steroidal anti-inflammatory drugs.  In addition to being of immense value to clinicians, other health care professionals and researchers, this title will prove invaluable for those taking undergraduate and graduate courses in the biomedical sciences and will also serve as a useful text for students of medicine, pharmacy, nursing and dentistry.
 
 
 
 

Caracteristici

The only book available that covers in a single volume the full range of drugs that provoke true (type 1) drug allergies
Written to appeal to both scientists and medical graduates
Content is relevant to practitioners right across the medical disciplines from surgeons to nurses, pharmacists and dentists
Of value clinically and in both teaching and research
Includes supplementary material: sn.pub/extras