Concise, yet comprehensive, coverage of various endoscopic forms as provided in this book will help the reader generate new knowledge in this field. Endoscopy has been in practice for many years in diagnostic medicine. From a simple image collection device, the endoscope has grown into an instrument that incorporates multiple imaging modalities to extract structural and functional information from different parts of the human body. Multimodality endoscopes are discussed in detail in this book, along with their clinical applications. The book is intended for graduate-level students as a quick reference to understand the evolving trends in endoscopic design research. The challenges that remain unaddressed could potentially be explored by biomedical researchers to advance this technology to realize the concept of optical biopsy during routine endoscopic examinations. The book portrays the endoscope as a purely optical instrument, and hence hybrid modes of endoscopic imaging are not covered.