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Excitatory Amino Acids: From Genes to Therapy de Peter H. Seeburg

Excitatory Amino Acids: From Genes to Therapy: Ernst Schering Foundation Symposium Proceedings, cartea 23

Editat de Peter H. Seeburg, Iris Bresink, Lechoslaw Turski
en Limba Engleză Paperback – 8 dec 2012
In this book emerging questions of current glutamate research are addressed and new pathways which glutamte research may take in the future discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotection and neurodegeneration.
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Specificații

ISBN-13: 9783662035986
ISBN-10: 3662035987
Pagini: 224
Ilustrații: XII, 210 p. 108 illus., 5 illus. in color.
Greutate: 0.27 kg
Ediția:Softcover reprint of the original 1st ed. 1998
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Ernst Schering Foundation Symposium Proceedings

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

1 Glutamate Receptor Channels, RNA Editing, and Epilepsy.- 2 Regulation of Glutamate Receptor Gene Expression in Global Ischemia.- 3 Factors Regulating Excitotoxic Neurodegeneration: The Role of Calcium and the Mitochondria.- 4 Excitotoxicity, Genetics, and Neurodegeneration in Amyotrophic Lateral Sclerosis.- 5 NO-NMDA Receptor Interactions: A Neuromolecular Approach to Novel Therapeutics.- 6 Glutamate in Neurodegenerative Disorders: Phenotype Resulting from Decreased Expression of AMPA Receptor GIuR-B Subunit mRNA in Rats.- 7 Quantitative Estimation of NMDA Receptor-Mediated Ca2+ Entry in Central Neurons.- 8 Calcium Permeability of Glutamate-Gated Channels in the CNS: Functional Role of the Ca2+-Permeable AMPA Receptor Channels.- 9 Localisation and Surface Expression of the AMPA Receptor Subunit GluR1 Using Green Fluorescent Protein and Anti-Peptide Antibodies.- 10 Input- and Output-Specific Segregation of Amino Acid Neurotransmitter Receptors on the Surface of Central Neurones.- Previous Volumes Published in this Series.

Textul de pe ultima copertă

Ernst Schering Research Foundation Workshop 23 Excitatory Amino Acids: From Genes to Therapy Editors: P. Seeburg, I. Bresink, L. Turski In this book emerging questions of current glutamate research are addressed and new pathways which glutamate research may take in the future discussed. Since glutamate antagonists are still the major hope for the therapy of neurodegenerative disorders in humans, research activities dedicated towards the development of such novel drugs are the focus of public attention. The book comments on the most recent discoveries in the field of neuroprotection and neurodegeneration.