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The Ubiquitin System in Health and Disease de Stefan Jentsch

The Ubiquitin System in Health and Disease: Ernst Schering Foundation Symposium Proceedings, cartea 2008/1

Editat de Stefan Jentsch, Bernhard Haendler
en Limba Engleză Hardback – 10 dec 2008
Descriere de la o altă ediție sau format:
The ubiquitin system plays an essential role in numerous cellular processes by controlling protein stability and function. A deregulation of this system has been reported in various pathologies including cancer, neurodegenerative diseases and immune disorders. This book presents the developments in this field.
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Specificații

ISBN-13: 9783540851066
ISBN-10: 3540851062
Pagini: 206
Ilustrații: XVI, 191 p. 39 illus., 32 illus. in color.
Dimensiuni: 130 x 210 x 23 mm
Greutate: 0.38 kg
Ediția:2009
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Ernst Schering Foundation Symposium Proceedings

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

Crosstalk Between the SUMO and Ubiquitin Pathways.- A Tale of Two Giant Proteases.- Molecular Genetics of the Ubiquitin-Proteasome System: Lessons from Yeast.- Less Is More: How Protein Degradation Regulates Muscle Development.- Transcriptional Control and the Ubiquitin–Proteasome System.- Ubiquitination of Myc: Proteasomal Degradation and Beyond.- Regulation of Apoptosis and Cytokinesis by the Anti-apoptotic E2/E3 Ubiquitin-Ligase BRUCE.- Dissecting Roles of Ubiquitination in the p53 Pathway.- Regulation of T Cell Differentiation and Allergic Responses by the E3 Ubiquitin Ligase Itch.- Approaches to Discovering Drugs that Regulate E3 Ubiquitin Ligases.- Inhibiting Hdm2 and Ubiquitin-Activating Enzyme: Targeting the Ubiquitin Conjugating System in Cancer.

Caracteristici

Latest findings in the field of ubiquitin and proteasome research Biochmemical, genetic and structural aspects are presented by top specialists to the field Includes supplementary material: sn.pub/extras