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Fibrinolytics and Antifibrinolytics de F. Bachmann

Fibrinolytics and Antifibrinolytics: Handbook of Experimental Pharmacology, cartea 146

Editat de F. Bachmann
en Limba Engleză Paperback – 27 feb 2012

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Specificații

ISBN-13: 9783642630293
ISBN-10: 3642630294
Pagini: 628
Ilustrații: XXVI, 599 p. 26 illus., 1 illus. in color.
Dimensiuni: 155 x 235 x 33 mm
Greutate: 0.87 kg
Ediția:Softcover reprint of the original 1st ed. 2001
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Handbook of Experimental Pharmacology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Professional/practitioner

Cuprins

Section I: Molecular Biology, Biochemistry, Physiology, and Pharmacology of the Plasminogen-Plasmin Enzyme System.- 1 The Fibrinolytic System and Thrombolytic Agents.- 2 Plasminogen and Streptokinase.- 3 Tissue-type Plasminogen Activator (tPA).- 4 Urinary-type Plasminogen Activator (uPA).- 5 The Inhibitors of the Fibrinolytic System.- 6 Assembly of the Plasminogen System on Cell Surfaces.- Section II: Clinical Use of Thrombolytic Agents.- In Acute Myocardial Infarction.- 7 Streptokinase and Anisoylated Lys-Plasminogen Streptokinase Activator Complex.- 8 Tissue-Type Plasminogen Activator (tPA).- 9 Urokinase and Single-Chain Urokinase-Type Plasminogen Activator (Pro-urokinase).- 10 Comparative Evaluations of tPA vs SK with Particular Reference to the GUSTO-I Trial.- 11 Conjunctive Therapy to Reduce the Occurrence of Coronary Reocclusion After Thrombolytic Treatment of AMI.- Thrombolytic Treatment of other Clinical Thromboembolic Conditions.- 12 New Concepts in Thrombolysis of Pulmonary Embolism.- 13 Deep Venous Thrombosis.- 14 Peripheral Arterial Occlusions.- 15 Thrombotic Cerebrovascular Disease.- Thrombolytic Agents in Development, Biochemistry, Pharmacology — Efficacy in Animal Experiments and First Clinical Trials.- 16 Staphylokinase.- 17 Desmodus rotundus (Common Vampire Bat) Salivary Plasminogen Activator.- 18 Thrombus-Targeting of Plasminogen Activators.- 19 The Hunt for the Ideal Thrombolytic Agent: Mutants of tPA and uPA, Chimera of Both Molecules, Fibrolase.- 20 Agents which Increase Synthesis and Release of Tissue-Type Plasminogen Activator.- Autifibrinolytic Agents.- 21 Structure, Pharmacology, and Clinical Use of Antifibrinolytic Agents.

Caracteristici

The main benefit for the reader of this new edition of this topic in the Handbook of Experimental Pharmacology series is that it is a modern up-to-date presentation of the entire field of the treatment of arterial and venous thromboses with thrombolytic agents - the previous edition, Vol 46, published in 1978, is therefore completely outdated