Hormone Receptors in Breast Cancer: Cancer Treatment and Research, cartea 147
Editat de Suzanne A. W. Fuquaen Limba Engleză Paperback – 20 oct 2014
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Specificații
ISBN-13: 9781489996800
ISBN-10: 148999680X
Pagini: 292
Ilustrații: X, 281 p.
Dimensiuni: 155 x 235 x 15 mm
Greutate: 0.41 kg
Ediția:2009
Editura: Springer Us
Colecția Springer
Seria Cancer Treatment and Research
Locul publicării:New York, NY, United States
ISBN-10: 148999680X
Pagini: 292
Ilustrații: X, 281 p.
Dimensiuni: 155 x 235 x 15 mm
Greutate: 0.41 kg
Ediția:2009
Editura: Springer Us
Colecția Springer
Seria Cancer Treatment and Research
Locul publicării:New York, NY, United States
Public țintă
Professional/practitionerCuprins
Hormone Action and Clinical Significance of the Estrogen Receptor #x03B1;.- Role of ER#x03B2; in Clinical Breast Cancer.- Hormone Action and Breast Cancer.- Estrogen Receptors in Breast Tumors of African American Patients.- BRCA1 Cross-Talk with Hormone Receptors.- Metastasis of Hormone Receptor Positive Breast Cancer.- Endocrine Therapy with Selective Estrogen Receptor Modulators (SERMs) and Aromatase Inhibitors in the Prevention and Adjuvant Therapy Settings.- Biomarkers in Neoadjuvant Trials.- Hormone Resistance.- Strategies of Hormonal Prevention.- Estrogen Receptor Phenotypes Defined by Gene Expression Profiling.
Textul de pe ultima copertă
This book provides an up-to-date resource of the role of hormone receptors in breast cancer written in depth for both the basic molecular academic researcher and translational scientist. Advances in basic science of molecular endocrinology have undoubtedly been translated into clinical practice, and clinicians caring for this disease need to be knowledgeable about these developments. The molecular basis of hormone action has been elucidated, and the relative significance of the different estrogen and progesterone receptor isoforms has been explored. This explosion of information has led to exciting new areas of gene specific targeting of the disease, and breast cancer prevention. Paradigm shifts in treatment options and sequencing have recently occurred in breast cancer management, necessitating close cooperation and communication between translational scientists and physicians. Hormone Receptors in Breast Cancer focuses on providing this communication.
"Hormones play an essential role in both the development of breast cancer and its therapy. This text provides a comprehensive review of the key receptors and signaling pathways that effect breast cancer growth leading figures in the field provide insight into the basic biology and clinical issues relevant to this devastating disease."
Steven T. Rosen, MD, Series Editor
"Hormones play an essential role in both the development of breast cancer and its therapy. This text provides a comprehensive review of the key receptors and signaling pathways that effect breast cancer growth leading figures in the field provide insight into the basic biology and clinical issues relevant to this devastating disease."
Steven T. Rosen, MD, Series Editor
Caracteristici
The book will be of value as a significant resource for the practicing clinician keeping abreast of the most current targeted and combination hormone therapies for breast cancer managment and prevention strategies.