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Human Genome Informatics: Translating Genes into Health de Christophe Lambert

Human Genome Informatics: Translating Genes into Health: Translational and Applied Genomics

Editat de Christophe Lambert, Darrol Baker, George P. Patrinos
en Limba Engleză Paperback – 8 aug 2018
Human Genome Informatics: Translating Genes into Healthexamines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented.
With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field.


  • Provides an overview of the most commonly used electronic tools to translate genomic information
  • Brings an update on the existing human genomic databases that directly impact genome interpretation
  • Summarizes and comparatively analyzes interpretation methods of whole genome data and their application in genomic medicine
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Specificații

ISBN-13: 9780128094143
ISBN-10: 0128094141
Pagini: 314
Dimensiuni: 191 x 235 x 21 mm
Editura: ELSEVIER SCIENCE
Seria Translational and Applied Genomics

Public țintă

graduate, doctoral and post-doctoral researchers in genome informatics and medical informatics; workers / representatives from bioinformatics companies and diagnostic laboratories interested in establishing informatics approaches to translate and interpret their findings.

Cuprins

1. Introduction 2. Interpretation of Cytogenetics data 3. Interpretation of microarray and transcriptomics data 4. Interpretation of whole exome and whole genome data 5. Artificial intelligence and translational tools 6. Translational tools for pharmacogenomics 7. Minimum information required for Pharmacogenomics experiments 8. Proteomics and metabolomics data analysis for translational medicine 9. Genome databases 10. Genomic data sharing 11. Genomics England as an example of genome informatics applications 12. Conclusions and future perspectives

Descriere

Human Genome Informatics: Translating Genes into Health examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented.
With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field.

 

 

 

  • Provides an overview of the most commonly used electronic tools to translate genomic information
  • Brings an update on the existing human genomic databases that directly impact genome interpretation
  • Summarizes and comparatively analyzes interpretation methods of whole genome data and their application in genomic medicine