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Economic Evaluation in Genomic and Precision Medicine: Translational and Applied Genomics

Christina Mitropoulou, Sarah Wordsworth, James Buchanan, George P. Patrinos
en Limba Engleză Paperback – 23 apr 2023
Economic Evaluation in Genomic and Precision Medicine provides an in-depth examination of essential concepts, protocols and applications of economic evaluation in genomic and precision medicine. Contributions from leading international medical geneticists and health economists compile new ways to effectively assess the costs and outcomes of different genomic care pathways, implement cost-effective medical interventions, and enhance the value of genomic and precision healthcare. Foundational chapters and discipline-specific case studies cover topics ranging from the economic analysis of genomic trial design, to health technology assessment of next-generation sequencing, ethical aspects, economic policy in genomic medicine, and pricing and reimbursement in clinical genomics.

  • Introduces clinicians, researchers and students to essential concepts, protocols and applications of economic evaluation in genomic and precision medicine
  • Demonstrates, through foundational chapters and discipline-specific case studies, how to assess the relative costs and outcomes of different genomic care pathways and implement cost-effective budgets
  • Establishes clear precedents on how genomic technologies can be leveraged to simultaneously reduce costs and enhance the value of healthcare
  • Features contributions from leading international medical geneticists and health economists that are actively evolved in economic assessments of genomic and precision medicine
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Specificații

ISBN-13: 9780128133828
ISBN-10: 0128133821
Pagini: 170
Dimensiuni: 191 x 235 x 11 mm
Greutate: 0.36 kg
Editura: ELSEVIER SCIENCE
Seria Translational and Applied Genomics


Public țintă

bioscientists; human geneticists; biotech industry professionals; undergraduate and graduate students in health economics and health sciences, namely medicine, pharmacy, genetics; clinicians and health managers; public health officers, health policy makers; governmental organizations; health care professionals; hospital managers

Cuprins

1. Introduction to economic evaluation in health sciences
2. Foundations of pharmacogenomics and personalized medicine
3. Economic evaluation of genome-guided treatment in oncology
4. Economic evaluation of rare diseases and the diagnostic odyssey
5. Economic analysis of pharmacogenetic testing for HLA-based adverse drug reactions
6. Economic evaluation of personalized medicine interventions in medium- and low-income countries with poor proliferation of genomics and genetic testing
7. Theoretical models for economic evaluation in genomic and personalized medicine
8. Using big data in economic evaluations in genomics: Challenges and opportunities
9. Assessing the stakeholder environment and views towards implementation of personalized medicine in a healthcare setting
10. Feasibility for pricing, budget allocation, and reimbursement of personalized medicine interventions