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Responsible Genomic Data Sharing: Challenges and Approaches

Editat de Xiaoqian Jiang, Haixu Tang
en Limba Engleză Paperback – 16 mar 2020
Responsible Genomic Data Sharing: Challenges and Approaches brings together international experts in genomics research, bioinformatics and digital security who analyze common challenges in genomic data sharing, privacy preserving technologies, and best practices for large-scale genomic data sharing. Practical case studies, including the Global Alliance for Genomics and Health, the Beacon Network, and the Matchmaker Exchange, are discussed in-depth, illuminating pathways forward for new genomic data sharing efforts across research and clinical practice, industry and academia.


  • Addresses privacy preserving technologies and how they can be applied to enable responsible genomic data sharing
  • Employs illustrative case studies and analyzes emerging genomic data sharing efforts, common challenges and lessons learned
  • Features chapter contributions from international experts in responsible approaches to genomic data sharing
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Specificații

ISBN-13: 9780128161975
ISBN-10: 0128161973
Pagini: 210
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE

Public țintă

Active clinical and translational researchers across genetics, genomics, molecular biology, molecular diagnostics, and bioinformatics; pharmacologists; genetic counselors
Students at the graduate level and above in genetics, genomics, bioinformatics, molecular biology, and pharmaceutical science

Cuprins

Section I: Privacy Challenges in Genomic Data Sharing 1. Criticality of Data Sharing in Genomic Research & Public views of genomic data sharing Gamze Gursoy 2. Genomic data access policy models Stephanie Dyke 3. Information leaks in aggregate genomic data, inference attacks Erman Ayday 4. Genealogical search using whole genome genotype profiles Yuan Wei, Ryan Lewis, Ardalan Naseri, Shaojie Zhang, Degui Zhi
Section II: Privacy-Preserving Techniques for Responsible Genomic Data Sharing 5. Homomorphic encryption Kim Laine 6. Secure Multiparty Computing (MPC) Yan Huang 7. Game-Theoretic Approaches (for Genomic Privacy) Zhiyu Wan 8. Hardware (SGX) Somnath Chakrabarti, Thomas Knauth, Dmitrii Kuvaiskii, Michael Steiner and Mona Vij