Inflammation in the Pathogenesis of Chronic Diseases: The COX-2 Controversy de Randall E. Harris

Inflammation in the Pathogenesis of Chronic Diseases: The COX-2 Controversy: Subcellular Biochemistry, cartea 42

en Limba Engleză Paperback – 22 noi 2010

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Specificații

ISBN-13: 9789048174294
ISBN-10: 9048174295
Pagini: 340
Ilustrații: XIV, 324 p.
Dimensiuni: 155 x 235 x 18 mm
Greutate: 0.48 kg
Ediția:Softcover reprint of hardcover 1st ed. 2007
Editura: SPRINGER NETHERLANDS
Colecția Springer
Seria Subcellular Biochemistry

Locul publicării:Dordrecht, Netherlands

Public țintă

Research

Cuprins

Historical Perspectives.- Anti-Inflammatory Drugs in the 21st Century.- Inflammatory Mechanisms of Pathogenesis.- Nitric Oxide Synthase and Cyclooxygenase Interactions in Cartilage and Meniscus.- Obesity, Inflammation, and Vascular Disease.- Cyclooxygenase-2 (COX-2) and the Inflammogenesis of Cancer.- Role of COX-2 in Inflammatory and Degenerative Brain Diseases.- Inflammation and Cardiovascular Disease: The Coxib Controversy.- Cardiovascular Effects of the Selective Cyclooxygenase-2 Inhibitors.- COX-2 Inhibitors And Cardiovascular Risk.- A Biological Rationale for the Cardiotoxic Effects of Rofecoxib.- Cox-2 Blockade in Cancer Prevention and Therapy.- Cancer Chemoprevention by Cyclooxygenase 2 (COX-2) Blockade.- Strategies for Colon Cancer Prevention.- Inflammation and Neurodegenerative Disease.- NSAIDs for the Chemoprevention of Alzheimer’s Disease.- Inflammation in parkinson’s disease.- Nutrition, Inflammation and Chronic Disease.- Essential Polyunsaturated Fatty Acids, Inflammation, Atherosclerosis and Cardiovascular Diseases.- Nutritional Intervention in Brain Aging.

Recenzii

From the reviews:“This is an up-to-date review of the current understanding of inflammation, the mechanisms by which it affects disease, and the role of anti-inflammatory medications pertaining to COX-2 and its inhibition. … Physicians and researchers with a particular interest in the current research and understanding of inflammation and COX-2 inhibition are the intended readers. … It is detailed, but written with great clarity and exhaustive references. It will be a great addition to any medical library.” (Vladimir N. Despotovic, Doody’s Review Service, February, 2010)

Caracteristici

A comprehensive treatise of COX-2, inflammation and disease A spell-binding look at the COX-2 controversy New and exciting findings on COX-2 blockade in cancer prevention and therapy as well as the prevention of Alzheimer’s disease and other neurodegenerative conditions COX-2 and the inflammogenesis of cancer

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