The intersection between knowledge management, computer science, and health care de?nes a technological area of great interest that has not been operated properly. Within this area medical procedures on preventive, diagnostic, the- peutic, or prognostic tasks in health careplay an outstanding role. The mana- ment of this type of knowledge at the point of care includes four technological scopes, at least. The ?rst one establishes the languages and structures to r- resent health care procedural knowledge and the integration of these structures with medical information systems. The second consists of the development of - gorithms and computer science technologies for the operation of this knowledge. The third scope is concerned with the development of methodologies to m- imize the bene?t of these algorithms and methodologies. The fourth concerns the integration of the previous algorithms, technologies, and methodologies in computer science systems that allow the application of this knowledge at the point of need, harnessing health care of greater quality and e?ciency.