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Macrophages: Origin, Functions and Biointervention: Results and Problems in Cell Differentiation, cartea 62

Editat de Malgorzata Kloc
en Limba Engleză Hardback – 11 mai 2017
This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine. 
Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus.
This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.
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Specificații

ISBN-13: 9783319540894
ISBN-10: 3319540890
Pagini: 416
Ilustrații: X, 376 p. 37 illus., 27 illus. in color.
Dimensiuni: 155 x 235 x 22 mm
Greutate: 0.72 kg
Ediția:1st ed. 2017
Editura: Springer International Publishing
Colecția Springer
Seria Results and Problems in Cell Differentiation

Locul publicării:Cham, Switzerland

Cuprins

Part A.Evolution, origin and fate of macrophages.- 1 Evolutionary aspects of Macrophages polarization.- 2Development and functional differentiation of tissue-resident vs. monocyte-derived macrophages in inflammatory reactions.- 3Hofbauer cells – placental macrophages of fetal origin.- 4Mesenchymal stem cells direct the immunological fate of macrophages.- 5  Monocyte/Macrophage - NK cell Cooperation: Old Tools for New Functions.- 6Macrophages in non-vertebrates: from insects and crustaceans to marine bivalves.- Part B.Immunobiology of macrophages.- 7F4/80 as a Major Macrophage Marker: The case of the Peritoneum and Spleen.- 8Immunobiology of Nitric Oxide and Regulation of Inducible Nitric Oxide Synthase.- 9Role for mechanotransduction in macrophage and dendritic cell immunobiology.- Part C.Role of macrophages in disease.- 10Macrophages’ Role in Tissue Disease and Regeneration.- 11Macrophages and their contribution to the development of atherosclerosis.- 12Macrophage Dysfunction in Respiratory Disease.- Part D.  Macrophages as a target for biointervention.- 13 Activation of macrophages in response to biomaterials.- 14 Macrophage differentiation in normal and accelerated wound healing.- 15 Macrophages and RhoA pathway in transplanted organs.
         





Notă biografică

Prior to completing her postdoctoral training in Canada, Dr. Kloc was a tenured Associate Professor in the Department of Zoology at the University of Warsaw, Poland. She also served as a Research Associate in the Department of Biology at Carleton University in Ottawa, Canada. While completing her postdoctoral training, Dr. Kloc earned the AHFMR Research Award from the University of Calgary and the MRC Biotechnology Training Award from Dalhousie University. She joined the University of Texas M.D. Anderson Cancer Center as a Research Scientist in the Department of Molecular Genetics in 1987, and became an Associate Professor in the Department of Biochemistry and Molecular Biology there in 2006. Dr. Kloc joined the Houston Methodist Research Institute in 2008. Currently, Dr. Kloc is the Weill Cornell Professor of Cell and Molecular Biology at The Houston Methodist Hospital and the Adjunct Professor at Department of Genetics, University of Texas, M D AndersonCancer Center.

Textul de pe ultima copertă

This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important components of modern medicine.
 
Macrophages are evolutionarily conserved phagocytotic cells. In recent years macrophages have emerged as one of the most versatile cells of immune system, which, depending on the milieu and circumstance, participate in development or inhibition of cancer, regeneration, wound healing, inflammation, organ rejection and interaction between mother and a fetus.

This book will be of particular interest to researchers working in immunology, cancer research, developmental biology, or related fields.

Caracteristici

Gives a state-of-the-art overview on macrophage functions Covers various aspects of macrophage development and formation Discusses possible roles of macrophages in disease and cancer Includes supplementary material: sn.pub/extras