This book critically explores from a comparative international perspective the role medicine plays in constructing and managing natural and social risks, including those belonging to modern medical technology and expertise. Drawing together chapters written by professional practitioners and social scientists from the UK, South America, Australia and Europe, the book offers readers an insightful and thought-provoking analysis of how modern medicine has transformed our understanding of both ourselves and the world around us, but in so doing has arguably failed to fully recognize and account for, its unintended and negative effects. This is an essential read for social scientists, practitioners and policymakers who want to better understand how they can develop new ways of thinking about how modern medicine can promote social goods and enhance public health.