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Membrane Structural Biology: With Biochemical and Biophysical Foundations

Autor Mary Luckey
en Limba Engleză Hardback – 23 feb 2014
This textbook provides a strong foundation and a clear overview for students of membrane biology and an invaluable synthesis of cutting-edge research for working scientists. The text retains its clear and engaging style, providing a solid background in membrane biochemistry, while also incorporating the approaches of biophysics, genetics and cell biology to investigations of membrane structure, function and biogenesis to provide a unique overview of this fast-moving field. A wealth of new high resolution structures of membrane proteins are presented, including the Na/K pump and a receptor-G protein complex, offering exciting insights into how they function. All key tools of current membrane research are described, including detergents and model systems, bioinformatics, protein-folding methodology, crystallography and diffraction, and molecular modeling. This comprehensive and up-to-date text, emphasising the correlations between membrane research and human health, provides a solid foundation for all those working in this field.
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Specificații

ISBN-13: 9781107030633
ISBN-10: 1107030633
Pagini: 423
Ilustrații: 184 b/w illus. 610 colour illus. 16 tables
Dimensiuni: 220 x 286 x 25 mm
Greutate: 1.38 kg
Ediția:Revised
Editura: Cambridge University Press
Colecția Cambridge University Press
Locul publicării:New York, United States

Cuprins

Dedication; Preface; 1. Introduction; 2. The diversity of membrane lipids; 3. Tools for studying membrane components; 4. Proteins in or at the bilayer; 5. Bundles and barrels; 6. Functions and families; 7. Protein folding and biogenesis; 8. Diffraction and simulation; 9. Membrane enzymes; 10. Membrane receptors; 11. Transporters; 12. Channels; 13. Electron transport and energy transduction; 14. In pursuit of complexity; Appendix I. Abbreviations; Appendix II. Single-letter codes for amino acids; Index.

Notă biografică


Descriere

An updated edition on membrane biology, providing new high resolution structures of membrane proteins and insights into how they function.