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Methylxanthines: Handbook of Experimental Pharmacology, cartea 200

Autor Bertil B. Fredholm
en Limba Engleză Paperback – 23 aug 2016
In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area.
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Specificații

ISBN-13: 9783662502303
ISBN-10: 3662502305
Pagini: 559
Ilustrații: XV, 559 p.
Dimensiuni: 155 x 235 mm
Greutate: 0.79 kg
Ediția:Softcover reprint of the original 1st ed. 2011
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Handbook of Experimental Pharmacology

Locul publicării:Berlin, Heidelberg, Germany

Cuprins

From the contents: Brief history of methylxanthine use. Distribution of methylxanthines in plants with comments on possible evolutionary origins. Pharmakokinetics and metabolism of natural methylxanthines in animals and man. Phosphodiesterase inhibition. Ryanodine receptors and calcium. Adenosine receptor antagonism. Theobromine and the pharmacology of cocoa. Pentoxifylline. Propentofylline. Methylxanthines, seizures and excitotoxicity. Methylxanthines and neurodegenerative disease. Methylxanthines and pain. Methylxanthines during pregnancy and early postnatal life. Methylxanthines and sleep. Methylxanthines and the kidney. Cardiovascular effects of methylxanthines. Methylxanthines in asthma. Methylxanthine effects on inflammatory cells. Methylxanthines, inflammation and cancer. Methylxanthines and drug dependence. Methylxanthines and reproduction. Methylxanthines and human health. Epidemiological and experimental evidence.

Caracteristici

21 contributions written by world experts in the field Provides an up-to-date and authoritative account of the pharmacology of methylxanthines Discusses the actions of the different xanthines and the mechanisms involved Includes supplementary material: sn.pub/extras