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Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics: Homogeneous and Heterogeneous Approaches de Panos Macheras

Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics: Homogeneous and Heterogeneous Approaches: Interdisciplinary Applied Mathematics, cartea 30

Autor Panos Macheras, Athanassios Iliadis
en Limba Engleză Paperback – 22 noi 2010
This book presents a novel modeling approach to biopharamceutics, pharmacokinetics and pharmacodynamic phenomena. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. Throughout, many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods.
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Specificații

ISBN-13: 9781441921000
ISBN-10: 1441921001
Pagini: 464
Dimensiuni: 155 x 235 x 24 mm
Greutate: 0.64 kg
Ediția:Softcover reprint of hardcover 1st ed. 2006
Editura: Springer
Colecția Springer
Seria Interdisciplinary Applied Mathematics

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

Basic Concepts.- The Geometry of Nature.- Diffusion and Kinetics.- Nonlinear Dynamics.- Modeling in Biopharmaceutics.- Drug Release.- Drug Dissolution.- Oral Drug Absorption.- Modeling in Pharmacokinetics.- Empirical Models.- Deterministic Compartmental Models.- Stochastic Compartmental Models.- Modeling in Pharmacodynamics.- Classical Pharmacodynamics.- Nonclassical Pharmacodynamics.

Recenzii

From the reviews:
"This book presents a novel modelling approach to biopharamceutics, pharmacokinetics and pharmacodynamic phenomena. … This state-of-the-art volume will be helpful to students and researchers in pharmacology, bioengineering, and physiology. This book is a must for pharmaceutical researchers to keep up with recent developments in this field." (P. R. Parthasarathy, Zentralblatt MATH, Vol. 1103 (5), 2007)

Textul de pe ultima copertă

The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods.
This timely and useful book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology.

Caracteristici

Brings together the disciplines of Biopharmaceutics, Pharmacokinetics and Pharmacodynamics (BPP)
Coveres the theory with specific examples behind all three under the perspective of heterogeneous processes while also treating the current state of the art in applied and theoretical BPP
Can serve as a text for graduate courses in bioengineering or BPP and as working tool for the empirical scientist who wants to expand into theory or the mathematician working in the biopharmaceutical field