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Navigating Endophytic Research for Next-Generation Therapeutics: Developments in Applied Microbiology and Biotechnology

Editat de Vagish Dwibedi, Neha Kapoor, Lokesh Gambhir, Swapnil Kajale
en Limba Engleză Paperback – 3 feb 2025
Navigating Endophytic Research for Next-Generation Therapeutics explores the dynamic and rapidly evolving field of endophytic fungal research and their application in combating diseases, addressing environmental challenges, and in shaping the future of therapeutics. The book starts off with a discussion on the biodiversity and biogeography of endophytic fungal communities and describes the bioprospecting of endophytes for drug discovery. The book also covers the therapeutic application of endophytic fungi to treat and manage specific diseases. It then investigates the innovative use of technologies such as genome editing, genetic engineering for enhanced bioactivity, multi-omics-based exploration, and the use of big data and machine learning in endophytic drug discovery. Featuring contributions from experts across fields like mycology, pharmacology, biotechnology, and environment science, this comprehensive, practical, and insightful resource guides those engaged in endophytic fungal research and its transformative potential in next-generation therapeutics.

  • Explores diverse research techniques for isolating, culturing, and characterizing endophytic fungi
  • Demonstrates how endophytic fungi have been successfully utilized in drug discovery and therapeutic applications
  • Recognizes the importance of responsible research practices and ethical considerations in bioprospecting and drug development
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Specificații

ISBN-13: 9780443314841
ISBN-10: 0443314845
Pagini: 400
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Seria Developments in Applied Microbiology and Biotechnology


Cuprins

1. Diversity and Biogeography of Endophytic Fungal Communities
2. Bioprospecting Ethnopharmacological Plants for Endophytic Fungal Drug Discovery
3. Biological Diversity Hotspots: Exploring Endophytic Fungi in Unique Ecosystems
4. Pharmaceutical Applications of Endophytic Fungi: Current Successes and Future Prospects
5. Endophytic Fungi in Anti-cancer Drug Development: Targeting Tumor Microenvironment
6. Neuropharmacology of Endophytic fungal Bioactives: Promising Leads for Brain Disorders
7. Antimicrobial Potential of Endophytic Fungal Compounds: Fighting Drug Resistance
8. Immunomodulatory Properties of Endophytic Fungi: Implications for Therapeutics
9. Antioxidant and Anti-inflammatory Endophytic Fungal Compounds for Chronic Diseases
10. Endophytic Fungi and Metabolic Disorders: From Diabetes to Obesity
11. Endophytic Fungi as Sources of Cardiovascular Drug Leads
12. Commercialization of Endophytic Fungal-Derived Therapeutics: Opportunities and Challenges
13. Clinical Trials and Commercialization of Endophytic Fungal-Derived Therapeutics
14. Endophytic Fungi and Multi-omics Integration: Data-Driven Drug Discovery
15. Endophytic Fungi in Aquatic Environments: Exploring Novel Drug Resources
16. Endophytic Fungi and Age-Related Diseases: Potential for Geriatric Therapeutics
17. Endophytic Fungi and Natural Insecticides: Eco-friendly Alternatives for Pest Control
18. Endophytic Fungal-Derived Antivirals: Expanding the Armamentarium Against Emerging Pathogens
19. Bioprospecting Extremophiles: Endophytic Fungi from Extreme Environments
20. Nanotechnology and Endophytic Fungi: Advancements in Drug Delivery and Targeting
21. Bioinformatics and Omics Tools in Endophytic Fungal Research
22. Genetic Engineering of Endophytic Fungi for Enhanced Bioactivity
23. Metabolomics and Natural Product Profiling of Endophytic Fungi
24. Big Data and Machine Learning in Endophytic Drug Discovery: Accelerating Innovations
25. Endophytic Fungi from Marine Environment and their Bio-Actives, Genome Editing, Endophytic Fungi for Biotransformation