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Observer Performance Methods for Diagnostic Imaging: Foundations, Modeling, and Applications with R-Based Examples: Imaging in Medical Diagnosis and Therapy

Autor Dev P. Chakraborty
en Limba Engleză Paperback – 31 mar 2021
"This book presents the technology evaluation methodology from the point of view of radiological physics and contrasts the purely physical evaluation of image quality with the determination of diagnostic outcome through the study of observer performance. The reader is taken through the arguments with concrete examples illustrated by code in R, an open source statistical language."
–  from the Foreword by Prof. Harold L. Kundel, Department of Radiology, Perelman School of Medicine, University of Pennsylvania


"This book will benefit individuals interested in observer performance evaluations in diagnostic medical imaging and provide additional insights to those that have worked in the field for many years."
– Prof. Gary T. Barnes, Department of Radiology, University of Alabama at Birmingham




This book provides a complete introductory overview of this growing field and its applications in medical imaging, utilizing worked examples and exercises to demystify statistics for readers of any background. It includes a tutorial on the use of the open source, widely used R software, as well as basic statistical background, before addressing localization tasks common in medical imaging. The coverage includes a discussion of study design basics and the use of the techniques in imaging system optimization, memory effects in clinical interpretations, predictions of clinical task performance, alternatives to ROC analysis, and non-medical applications.



Dev P. Chakraborty, PhD, is a clinical diagnostic imaging physicist, certified by the American Board of Radiology in Diagnostic Radiological Physics and Medical Nuclear Physics. He has held faculty positions at the University of Alabama at Birmingham, University of Pennsylvania, and most recently at the University of Pittsburgh.


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Specificații

ISBN-13: 9780367781637
ISBN-10: 0367781638
Pagini: 590
Dimensiuni: 178 x 254 x 30 mm
Greutate: 0.45 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Imaging in Medical Diagnosis and Therapy


Public țintă

Academic and Professional Practice & Development

Cuprins

1 Preliminaries




PART A The receiver operating characteristic (ROC) paradigm


2 The binary paradigm


3 Modeling the binary task


4 The ratings paradigm


5 Empirical AUC


6 Binormal model


7 Sources of variability in AUC




PART B Two significance testing methods for the ROC paradigm


8 Hypothesis testing


9 Dorfman–Berbaum–Metz–Hillis (DBMH) analysis


10 Obuchowski–Rockette–Hillis (ORH) analysis


11 Sample size estimation




PART C The free-response ROC (FROC) paradigm


12 The FROC paradigm


13 Empirical operating characteristics possible with FROC data


14 Computation and meanings of empirical FROC FOM-statistics and AUC measures


15 Visual search paradigms


16 The radiological search model (RSM)


17 Predictions of the RSM


18 Analyzing FROC data


19 Fitting RSM to FROC/ROC data and key findings




PART D Selected advanced topics


20 Proper ROC models


21 The bivariate binormal model


22 Evaluating standalone CAD versus radiologists


23 Validating CAD analysis

Notă biografică

Dev P. Chakraborty received his PhD in physics in 1977 from the University of Rochester, NY. Following postdoctoral fellowships at the University of Pennsylvania (UPENN) and the University of Alabama at Birmingham (UAB), since 1982 he has worked as a clinical diagnostic imaging physicist. He is American Board of Radiology certified in Diagnostic Radiological Physics and Medical Nuclear Physics (1987). He has held faculty positions at UAB (1982 - 1988), UPENN (1988-2002) and the University of Pittsburgh (2002-2016). At UPENN he supervised hospital imaging equipment quality control, resident physics instruction and conducted independent research. He is an author on 78 peer-reviewed publications, the majority of which are first-authored. He has received research funding from the Whittaker Foundation, the Office of Women's Health, the FDA, the DOD, and has served as principal investigator on several NIH RO1 grants.

Recenzii

"This book will benefit individuals interested in observer performance evaluations in diagnostic medical imaging and provide additional insights to those that have worked in the field for many years."
— from the Foreword by Gary T. Barnes, Professor Emeritus, Department of Radiology, University of Alabama Birmingham
"As opposed to most of the books with a primary statistical orientation, this book presents the technology evaluation methodology from the point of view of radiological physics and contrasts the purely physical evaluation of image quality with the determination of diagnostic outcome through the study of observer performance. The reader is taken through the arguments with concrete examples illustrated by code in R, an open source statistical language."
—Harold L. Kundel, Emeritus Professor, Department of Radiology, Perelman School of Medicine, University of Pennsylvania

Descriere

This book provides a complete, introductory overview of this growing field and its applications in medical imaging, utilizing worked examples and exercises to demystify statistics for readers of any background. It covers discussion of study design basics and use of the techniques in imaging system optimization, among other topics.