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Particulate Interactions in Dry Powder Formulation for Inhalation

Autor Xian Ming Zeng, Gary Peter Martin, Christopher Marriott
en Limba Engleză Hardback – 26 oct 2000
Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles and factors in pharmaceutical powder technology, critically reviews some of the studies carried out in dry powder formulation development, and proposes possible strategies for improving their efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).
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Specificații

ISBN-13: 9780748409600
ISBN-10: 0748409602
Pagini: 272
Dimensiuni: 174 x 246 x 19 mm
Greutate: 0.68 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press

Public țintă

Academic and Professional Practice & Development

Cuprins

1. Interparticulate Forces 2. Interparticulate Forces in Pharmaceutical Powders 3. Medicinal Aerosols 4. Particle Interactions with Air Streams 5. Particulate Interactions in Dry Powder Aerosols 6. Measurement of Cohesion, Adhesion and Dispersion of Powders 7. Physical Characterisation of Pharmaceutical Powders

Notă biografică

Zeng, Xian Ming; Martin, Gary Peter; Marriott, Christopher

Descriere

Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles established in surface and colloidal chemistry with pharmaceutical powder technology. It discusses some of the factors affecting particulate interactions, and particle-fluid interaction in the respiratory tract. It review some of the studies carried out in dry powder formulation development, and proposes possible strategies in improving DPI efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).