Cantitate/Preț
Produs
Total produse
Vezi coșul
Pharmacotherapeutics of the Thyroid Gland de A.P. Weetman

Pharmacotherapeutics of the Thyroid Gland: Handbook of Experimental Pharmacology, cartea 128

Editat de A.P. Weetman, Ashley Grossman
en Limba Engleză Paperback – 19 ian 2012
All the important pharmacological interactions affecting thyroid function are described in this book. The first section is devoted to the physiology and biochemistry of thyroid disease, putting the pharmacological interactions into perspective. The second section reviews all the important pharmacological effects on thyroid function and also deals with the impact of other environmental agents. The chapters are written by internationally recognised experts and extensively referenced to provide an up-to-date review of the pharmacological interactions important to the thyroid and its diseases.
Citește tot Restrânge

Din seria Handbook of Experimental Pharmacology

  • 5% Bacterial Protein Toxins
    Preț: 142504 lei
  • 5% Therapeutic Antibodies
    Preț: 90742 lei
  • 5% Adenosine Receptors in Health and Disease
    Preț: 351778 lei
  • 5% Urinary Tract
    Preț: 73030 lei
  • 5% New Approaches to Drug Discovery
    Preț: 142597 lei
  • 5% Metabolic Control
    Preț: 143528 lei
  • 5% Adhesion G Protein-coupled Receptors: Molecular, Physiological and Pharmacological Principles in Health and Disease
    Preț: 143052 lei
  • 5% The Actin Cytoskeleton
    Preț: 193069 lei
  • 5% Free Fatty Acid Receptors
    Preț: 192247 lei
  • 5% Pharmacology of Mitochondria
    Preț: 193746 lei
  • 5% Histamine and Histamine Receptors in Health and Disease
    Preț: 211758 lei
  • 5% Pharmacologic Therapy of Ocular Disease
    Preț: 211996 lei
  • 5% Targeting Trafficking in Drug Development
    Preț: 211738 lei
  • 5% New Psychoactive Substances: Pharmacology, Clinical, Forensic and Analytical Toxicology
    Preț: 108815 lei
  • 5% Botulinum Toxin Therapy
    Preț: 109827 lei
  • 5% Organotypic Models in Drug Development
    Preț: 142029 lei
  • 5% Organic Cation Transporters in the Central Nervous System
    Preț: 110484 lei
  • 5% Pharmacology of Immunosuppression
    Preț: 110484 lei
  • 5% Physiology, Pharmacology and Pathology of the Blood-Brain Barrier
    Preț: 110814 lei
  • 5% Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease
    Preț: 110669 lei
  • 5% Sex and Gender Effects in Pharmacology
    Preț: 110577 lei
  • 5% Drug Delivery and Targeting
    Preț: 117435 lei
  • 5% Erzeugung von Krankheitszuständen durch das Experiment: Teil 11A Infektionen III
    Preț: 40848 lei
  • 5% Morphin und Morphinähnlich Wirkende Verbindungen
    Preț: 40963 lei
  • 5% Die Pharmakologie Anorganischer Anionen: Die Hofmeistersche Reihe
    Preț: 53989 lei
  • 5% Targeted Drug Delivery
    Preț: 72047 lei
  • 5% Biochemical Pharmacology of Blood and Bloodforming Organs
    Preț: 73309 lei
  • 5% Physiology and Pharmacology of the Blood-Brain Barrier
    Preț: 73127 lei
  • 5% Opioids I
    Preț: 74643 lei
  • 5% Opioids II
    Preț: 74772 lei
  • 5% Gastrointestinal Regulatory Peptides
    Preț: 72524 lei
  • 5% Physiology and Pharmacology of Bone
    Preț: 74280 lei
  • 5% GTPases in Biology I
    Preț: 39323 lei
  • 5% GTPases in Biology II
    Preț: 73566 lei
  • 5% Principles and Treatment of Lipoprotein Disorders
    Preț: 72833 lei
  • 5% Lobelin und Lobeliaalkaloide
    Preț: 38952 lei
  • 5% Pharmacokinetics of Drugs
    Preț: 73071 lei
  • 5% Pharmacology of Smooth Muscle
    Preț: 74058 lei
  • 5% Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity
    Preț: 73019 lei
  • 5% The Pharmacology of Monoclonal Antibodies
    Preț: 72342 lei
  • 5% The Pharmacology of Alcohol Abuse
    Preț: 73127 lei
  • 5% Toxicology of Metals: Biochemical Aspects
    Preț: 72668 lei
  • 5% The Pharmacology of Sleep
    Preț: 351649 lei
  • 5% Diuretics
    Preț: 72926 lei
  • 5% Pharmacological Aspects of Drug Dependence: Toward an Integrated Neurobehavioral Approach
    Preț: 73711 lei
  • 5% Antipsychotics
    Preț: 73092 lei
  • 5% Drug-Induced Hepatotoxicity
    Preț: 73878 lei
  • 5% Mechanisms of Drug Interactions
    Preț: 90994 lei
  • 5% Glucagon III
    Preț: 72010 lei

Preț: 72105 lei

Preț vechi: 75899 lei
-5% Nou

Puncte Express: 1082
Preț estimativ în valută:
13799€ • 14236$ • 11679£

Carte tipărită la comandă

Livrare economică 05-19 martie

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă
Preluare comenzi: 021 569.72.76

Specificații

ISBN-13: 9783642645198
ISBN-10: 3642645194
Pagini: 392
Ilustrații: XVIII, 370 p.
Dimensiuni: 155 x 235 x 21 mm
Greutate: 0.55 kg
Ediția:Softcover reprint of the original 1st ed. 1997
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Handbook of Experimental Pharmacology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Professional/practitioner

Cuprins

1 Introduction: Clinical Aspects of Thyroid Treatment.- A. Introduction.- B. Choices of Treatment for the Hyperthyroidism of Graves’ Disease.- C. Subclinical Hyperthyroidism.- D. Correct Dose of Thyroxine in Primary Hypothyroidism.- E. Subclinical Hypothyroidism: Treatment or Not?.- References.- 2 Control of TRH and TSH Secretion.- A. Introduction.- B. Negative Feedback Action of Thyroid Hormones.- C. Structure and Actions of TRH.- D. Structure and Actions of Somatostatin.- E. Actions of Neurotransmitters.- F. Actions of Cytokines and Inflammatory Mediators.- G. Physiological and Secondary TSH Changes.- References.- 3 The TSH Receptor.- A. Introduction.- B. TSH Receptor Cloning.- C. Structure of the TSHR in the Human Thyroid Gland.- D. Structure of the TSHR in Transfected Cells.- E. Controversies on Receptor Structure.- F. Expression of the TSH Receptor in the Baculovirus System.- G. Shedding of TSH Receptor Ectodomain in Thyroid and Transfected Cells.- H. Cellular Expression of the TSH Receptor.- I. Intracellular Trafficking of the Receptor.- J. Structure-Function Relationships.- K. Gene Structure and Regulation.- L. The TSH Receptor and Pathology.- M. Conclusions.- References.- 4 Thyroid Hormone Synthesis, Plasma Membrane Transport and Metabolism.- A. Thyroid Hormone Synthesis.- B. Thyroid Hormone Plasma Membrane Transport.- C. Thyroid Hormone Metabolism.- D. Deiodination.- E. Characterization of Iodothyronine Deiodinases.- F. Sulphation.- G. Glucuronidation.- References.- 5 Thyroid Hormone Transport.- A. Introduction.- B. Serum Bingding in Humans.- C. Binding Kinetics.- D. Free Hormone Measurement.- E. Interactions with Competitors.- References.- 6 Molecular Biology of Thyroid Hormone Action.- A. Introduction.- B. Extranuclear Mechanisms of Thyroid Hormone Action.-C. Identification of High-Affinity Nuclear-Binding Sites for Thyroid Hormones.- D. Cloning of cDNAs Encoding Nuclear Receptors for T3.- E. Recognition of Two Genes Encoding Two Major Classes of TR.- F. Thyroid Hormone Response Elements.- G. Structural Characteristics of TRs and Identification of Functional Domains.- H. Role of the TR Splice Variant TR?2.- References.- 7 Iodine: Metabolism and Pharmacology.- A. Introduction.- B. Iodide Transport and Organification.- C. Thyroid Autoregulation.- References.- 8 Antithyroid Drugs: Their Mechanism of Action and Clinical Use.- A. Introduction.- B. Hyperthyroidism.- C. Pharmacokinetics.- D. Mechanism of Action.- E. Clinical Use.- F. Conclusions.- References.- 9 Effect of Lithium on the Thyroid Gland.- A. Introduction.- B. Effect on Thyroid Physiology.- C. Effect on the Hypothalamic-Pituitary Axis.- D. Lithium and Cell Function.- E Immunological Effects on Thyroid Function.- F. Effect on Thyroid Hormone Action.- G. Clinical Effects on the Thyroid.- H. Clinical Use in Thyroid Disease.- References.- 10 Amiodarone and the Thyroid.- A. Pharmacology of Amiodarone.- B. Effects of Amiodarone on Thyroid Hormone Secretion and Metabolism.- C. Amiodarone-Induced Thyrotoxicosis and Amiodarone-Induced Hypothyroidism.- D. Amiodarone as a Thyroid Hormone Antagonist.- References.- 11 Effects of Other Pharmacological Agents on Thyroid Function.- A. Introduction.- B. Effects of Various Drugs on Thyroidal Hormonogenesis.- C. Effects of Drugs on Thyroid Hormone Metabolism.- D. Drug Effects on Cellular and Intestinal Uptake of Thyroid Hormone.- References.- 12 Effects of Environmental Agents on Thyroid Function.- A. Introduction.- B. Chemical Categories, Sources, Pharmacokinetics, and Mechanism of Action.- References.- 13 Thyroid HormoneAntagonism.- A. Introduction.- B Inhibition of Uptake.- C. Cytoplasmic Binding.- D. Antagonism at the Receptor Level.- References.- 14 Immunomodulatory Agents in Autoimmune Thyroid Disease.- A. Introduction.- B. Hormones and Autoimmune Thyroid Disease.- C. Toxins and Autoimmune Thyroid Disease.- D. Trace Elements and Autoimmune Thyroiditis.- E. Drugs and Autoimmune Thyroid Disease.- F. Cytokines and Autoimmune Thyroid Disease.- G. Immunomodulatory Agents in TAO.- References.