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Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume 2

Editat de Amit Kumar Nayak, Kalyan Kumar Sen
en Limba Engleză Paperback – 14 aug 2024
Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics.

In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence.


  • Provides extensive details on the most recent developments in biopharmaceutics
  • Contains contributions from leading experts from academia, research, industry and regulatory agencies
  • Includes high quality illustrations, flow charts and tables for easier understanding of the concepts
  • Discusses practical examples and research case studies
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Specificații

ISBN-13: 9780323918183
ISBN-10: 0323918182
Pagini: 486
Dimensiuni: 216 x 276 mm
Greutate: 0.45 kg
Editura: ELSEVIER SCIENCE

Public țintă

Postgraduate pharmacy students, doctoral and postdoctoral research fellows, pharmaceutical formulators, scientists, researchers, and regulatory scientists; Researchers and postgraduate students in biotechnology, biomedical sciences and engineering, bioengineering sciences, chemical engineering

Cuprins

Section I: Physico-chemical aspects of dosage forms
1. Physico-chemical factors influencing drug degradation
2. Stability and accelerated stability studies of dosage forms
3. Solubility of drugs
4. Drug dissolution studies of pharmaceutical formulations
5. Pharmaceutical granulation: Engineering perspective and futuristic trends
6. Tablet compression and consolidation: Theory and applications

Section II: Biopharmaceutics
7. Introduction to Biopharmaceutics
8. Gastrointestinal absorption of drugs
9. Routes of drug administration and their impact in biopharmaceutics
10. Drug elimination and renal excretion of drugs
11. Membrane transport and permeation of drugs
12. Factors affecting drug absorption and disposition
13. Bioavailability and bioequivalence
14. Contribution of biopharmaceutics and pharmacokinetics to improve drug therapy
15. Dosage regimen
16. Multicompartment models
17. Nonlinear pharmacokinetics
18. Computer-aided biopharmaceutical model development
19. Computer simulations in pharmacokinetics
20. WHO and ICH Guidelines for ‘Good Manufacturing Practices’
21. Pilot plant scale up techniques in pharmaceutical product development
22. Advances in solid dosage forms