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Protein Engineering for Therapeutics, Part B de K. Dane Wittrup

Protein Engineering for Therapeutics, Part B: Methods in Enzymology, cartea 503

K. Dane Wittrup, Gregory L. Verdine
en Limba Engleză Hardback – 27 feb 2012
This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Peptides, and Scaffolds


  • Chapters provide an invaluable resource for academics, researchers and students alike
  • Iinternational board of authors
  • This volume is split into sections that cover subjects such as peptides, and scaffolds
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Specificații

ISBN-13: 9780123969620
ISBN-10: 012396962X
Pagini: 392
Dimensiuni: 152 x 229 x 25 mm
Greutate: 0.77 kg
Editura: ELSEVIER SCIENCE
Seria Methods in Enzymology

Public țintă

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists

Cuprins

Part III: Peptides
1. Stapled Peptides for Intracellular Drug Targets
2. Mapping of vascular zip codes by phage display
3. Engineering cyclic peptide toxins
4. Peptide Discovery using Bacterial Display and Flow Cytometry

Part V: Scaffolds
5. Designed Ankyrin Repeat Proteins (DARPins): From research to therapy
6. Target-binding proteins based on the tenth human fibronectin type III domain (10Fn3)
7. Anticalins: small engineered binding proteins based on the lipocalin scaffold
8. T Cell Receptor Engineering
9. Engineering Knottins as Novel Binding Agents

Part VI: Pharmacokinetics
10. Practical Theoretic Guidance for the Design of Tumor Targeting Agents
11. Re-Engineering Biopharmaceuticals for Targeted Delivery Across the Blood-Brain Barrier
12. Engineering and Identifying Supercharged Proteins for Macromolecule Delivery into Mammalian Cells