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Quasispecies: Concept and Implications for Virology de Esteban Domingo

Quasispecies: Concept and Implications for Virology: Current Topics in Microbiology and Immunology, cartea 299

Editat de Esteban Domingo
en Limba Engleză Paperback – 12 feb 2010
Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.
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Specificații

ISBN-13: 9783642065828
ISBN-10: 3642065821
Pagini: 424
Ilustrații: XI, 410 p.
Dimensiuni: 155 x 235 x 22 mm
Ediția:2006
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Current Topics in Microbiology and Immunology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

What Is a Quasispecies?.- Quasispecies in Time-Dependent Environments.- Viruses as Quasispecies: Biological Implications.- Virus Fitness: Concept, Quantification, and Application to HIV Population Dynamics.- Population Bottlenecks in Quasispecies Dynamics.- Evolutionary Dynamics of HIV-1 and the Control of AIDS.- Evolution of Virulence in Picornaviruses.- Molecular Mechanisms of Poliovirus Variation and Evolution.- Hepatitis C Virus Population Dynamics During Infection.- Evolutionary Influences in Arboviral Disease.- Arenavirus Diversity and Evolution: Quasispecies In Vivo.- Mutant Clouds and Occupation of Sequence Space in Plant RNA Viruses.- Parvovirus Variation for Disease: A Difference with RNA Viruses?.- Transitions in Understanding of RNA Viruses: A Historical Perspective.

Caracteristici

Begins from the understanding that virus variation and selection in virus subpopulations are intimately related to viral disease mechanisms A central topic is the origin of the quasispecies concept Examines the implications of quasispecies dynamics for viral populations Presents and analyzes vital new research in the evolution of viral diseases Includes supplementary material: sn.pub/extras