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Sex and Gender Differences in Infection and Treatments for Infectious Diseases de Sabra L. Klein

Sex and Gender Differences in Infection and Treatments for Infectious Diseases: Current Topics in Microbiology and Immunology, cartea 441

Editat de Sabra L. Klein, Craig W. Roberts
en Limba Engleză Hardback – 12 sep 2023
This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents.
This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).

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Paperback (1) 114409 lei  6-8 săpt.
  Springer International Publishing – 22 oct 2016 114409 lei  6-8 săpt.
Hardback (1) 126835 lei  6-8 săpt.
  Springer International Publishing – 12 sep 2023 126835 lei  6-8 săpt.

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Specificații

ISBN-13: 9783031351389
ISBN-10: 303135138X
Ilustrații: VI, 280 p. 14 illus., 13 illus. in color.
Dimensiuni: 155 x 235 mm
Greutate: 0.58 kg
Ediția:2nd ed. 2023
Editura: Springer International Publishing
Colecția Springer
Seria Current Topics in Microbiology and Immunology

Locul publicării:Cham, Switzerland

Cuprins

Genetics of sex differences in immunity.- The influence of sex hormones and X chromosome in immune responses.- Sex Differences in HIV Infection.- Chapter 6: Effects of Biological Sex and Pregnancy on SARS-CoV-2 Pathogenesis and Vaccine Outcomes.- Biological sex and pregnancy affect influenza pathogenesis and vaccination.- Sex and gender differences in tuberculosis pathogenesis and treatment outcomes.- Sex-Linked Differences in Malaria Risk Across the Lifespan.- Sex Difference in Amebiasis.- Sex Differential and Non-Specific Effects of Vaccines Over the Life Course.- Immunology of pregnancy and systemic consequences.

Notă biografică

Dr. Sabra Klein, Ph.D. is a Professor of Molecular Microbiology & Immunology, Biochemistry & Molecular Biology, and International Health at the Johns Hopkins Bloomberg School of Public Health and Department of Medicine at the Johns Hopkins School of Medicine. She is an expert on sex differences in immune responses to pathogens and vaccines, with interrogation of sex-specific effects of aging as well as pregnancy in humans and animal models. She currently has over 185 peer-reviewed publications, authored several book chapters, and edited three books on the broad topics of sex differences in response to infection and treatments for infectious diseases. During the 2009 influenza pandemic, she was commissioned by the WHO to evaluate and publish a report on the impact of sex, gender, and pregnancy on the outcome of influenza virus infection. During the current COVID-19 pandemic, Dr. Klein wrote commentaries for several journals and was interviewed by several major news media outletsabout sex differences in immunity, disease outcomes, and responses to vaccines. She is a fellow of the American Academy of Microbiology and the American Association for the Advancement of Science. In 2023, she received the NIH Vivian Pinn Award for Outstanding Research in Women’s Health.
Dr. Craig W. Roberts, Ph.D. is a Professor of Parasitology, at the Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde. He is an infectious disease expert having worked with viral, bacterial and parasitic pathogens.  He has contributed to our understanding of the pathogenesis of infectious diseases and how they can be controlled through better antimicrobials and vaccines.  He has a long-standing interest in the influence of sex and pregnancy-associated hormones on the immune response and how this, in turn influences the pathogenesis of disease. He has published on how Toxoplasma gondii infection can affect the maternal foetal interface and the outcome of pregnancy. He has co-written a book on the biology of parasites and co-edited 2 books exploring the influence of sex hormones and gender on the immune response and treatment of infectious diseases. 

Textul de pe ultima copertă

This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents.
This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).

Caracteristici

Fully revised and significantly extended second edition Explores how biological sex and gender impact innate and adaptive immune responses Discusses reactions to vaccines in different sexes and pregnant individuals

Recenzii

“The intended audience is basic science and clinicalresearchers in the fields of microbiology, immunology, and pharmacology.Practitioners of personalized medicine will find this book helpful inunderstanding the mechanisms and factors that lead to sex-specific responses totreatment of infectious diseases and vaccinations. … This unique book providesa comprehensive series of up-to-date reviews by experts on sex and genderdifferences in immunology and infectious diseases.” (Robert Gene Penn, Doody’sBook Reviews, February, 2016)